R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

Item
http://www.wikidata.org/entity/Q41788699
The Role of Pontin and Reptin in Cellular Physiology and Cancer Etiology.Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.The Sm-core mediates the retention of partially-assembled spliceosomal snRNPs in Cajal bodies until their full maturation.RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.Bi-allelic Mutations in EPRS, Encoding the Glutamyl-Prolyl-Aminoacyl-tRNA Synthetase, Cause a Hypomyelinating Leukodystrophy.The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones.Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP.
P2860

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

Item
http://www.wikidata.org/entity/Q41788699
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
R2TP/Prefoldin-like component ...... all nuclear ribonucleoprotein.
@en
type
label
R2TP/Prefoldin-like component ...... all nuclear ribonucleoprotein.
@en
prefLabel
R2TP/Prefoldin-like component ...... all nuclear ribonucleoprotein.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
R2TP/Prefoldin-like component ...... all nuclear ribonucleoprotein.
@en
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P698
P921
P932