cAMP activates TRPC6 channels via the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB)-mitogen-activated protein kinase kinase (MEK)-ERK1/2 signaling pathway.
about
cAMP and Ca²⁺ signaling in secretory epithelia: crosstalk and synergism.cAMP signaling prevents podocyte apoptosis via activation of protein kinase A and mitochondrial fusion.Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cellsGain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2)Attenuated mesangial cell proliferation related to store-operated Ca2+ entry in aged rat: the role of STIM 1 and Orai 1Lychee Seed Saponins Improve Cognitive Function and Prevent Neuronal Injury via Inhibiting Neuronal Apoptosis in a Rat Model of Alzheimer's Disease.Novel cAMP signalling paradigms: therapeutic implications for airway diseaseOrai1 forms a signal complex with BKCa channel in mesenteric artery smooth muscle cells.Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels.Involvement of phosphoinositide 3-kinase and PTEN protein in mechanism of activation of TRPC6 protein in vascular smooth muscle cells.Computational modeling predicts the ionic mechanism of late-onset responses in unipolar brush cells.Contrasting Patterns of Agonist-induced Store-operated Ca2+ Entry and Vasoconstriction in Mesenteric Arteries and Aorta With Aging.cAMP Signaling of Adenylate Cyclase Toxin Blocks the Oxidative Burst of Neutrophils through Epac-Mediated Inhibition of Phospholipase C Activity.The role of eNOS phosphorylation in causing drug-induced vascular injury.The human transient receptor potential vanilloid 3 channel is sensitized via the ERK pathway.Adenosine modulates light responses of rat retinal ganglion cell photoreceptors througha cAMP-mediated pathway.Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.Trpc6 inactivation confers protection in a model of severe nephrosis in rats.Permeation and Rectification in Canonical Transient Receptor Potential-6 (TRPC6) Channels
P2860
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P2860
cAMP activates TRPC6 channels via the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB)-mitogen-activated protein kinase kinase (MEK)-ERK1/2 signaling pathway.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
cAMP activates TRPC6 channels ...... MEK)-ERK1/2 signaling pathway.
@en
type
label
cAMP activates TRPC6 channels ...... MEK)-ERK1/2 signaling pathway.
@en
prefLabel
cAMP activates TRPC6 channels ...... MEK)-ERK1/2 signaling pathway.
@en
P2093
P2860
P50
P356
P1476
cAMP activates TRPC6 channels ...... (MEK)-ERK1/2 signaling pathway
@en
P2093
P2860
P304
19439-19445
P356
10.1074/JBC.M110.210294
P407
P577
2011-04-12T00:00:00Z