Conserved herpesviral kinase promotes viral persistence by inhibiting the IRF-3-mediated type I interferon response.
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Cloak and Dagger: Alternative Immune Evasion and Modulation Strategies of PoxvirusesDoes EBV alter the pathogenesis of malaria?Phosphoproteomic analyses reveal signaling pathways that facilitate lytic gammaherpesvirus replicationMurine gammaherpesvirus 68 encoding open reading frame 11 targets TANK binding kinase 1 to negatively regulate the host type I interferon responseMurine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replicationPhosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic SignalingThe murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcriptionSystematic identification of H274Y compensatory mutations in influenza A virus neuraminidase by high-throughput screening.The anti-interferon activity of conserved viral dUTPase ORF54 is essential for an effective MHV-68 infection.Murine gammaherpesvirus 68 has evolved gamma interferon and stat1-repressible promoters for the lytic switch gene 50.Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells.The varicella-zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3Global mRNA degradation during lytic gammaherpesvirus infection contributes to establishment of viral latency.High-throughput identification of loss-of-function mutations for anti-interferon activity in the influenza A virus NS segment.Murine gamma herpesvirus 68 hijacks MAVS and IKKβ to abrogate NFκB activation and antiviral cytokine production.Interplay between Kaposi's sarcoma-associated herpesvirus and the innate immune system.Noninvasive biophotonic imaging for studies of infectious disease.Mesenchymal stem cells detect and defend against gammaherpesvirus infection via the cGAS-STING pathway.Varicella-zoster virus infection triggers formation of an interleukin-1β (IL-1β)-processing inflammasome complexProteomic characterization of murid herpesvirus 4 extracellular virionsGammaherpesvirus gene expression and DNA synthesis are facilitated by viral protein kinase and histone variant H2AX.Tiled microarray identification of novel viral transcript structures and distinct transcriptional profiles during two modes of productive murine gammaherpesvirus 68 infection.Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma.A novel mechanism for the inhibition of interferon regulatory factor-3-dependent gene expression by human respiratory syncytial virus NS1 protein.Type I Interferons Direct Gammaherpesvirus Host ColonizationInhibition of cGAS DNA Sensing by a Herpesvirus Virion ProteinCoordinate regulation of DNA damage and type I interferon responses imposes an antiviral state that attenuates mouse gammaherpesvirus type 68 replication in primary macrophages.Subcapsular sinus macrophages limit acute gammaherpesvirus disseminationAtaxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection.Key motifs in EBV (Epstein-Barr virus)-encoded protein kinase for phosphorylation activity and nuclear localization.Discovery of a Coregulatory Interaction between Kaposi's Sarcoma-Associated Herpesvirus ORF45 and the Viral Protein Kinase ORF36.A viral kinase mimics S6 kinase to enhance cell proliferation.Suppression of TLR9 immunostimulatory motifs in the genome of a gammaherpesvirusType I Interferons and NK Cells Restrict Gammaherpesvirus Lymph Node Infection.Gammaherpesviral gene expression and virion composition are broadly controlled by accelerated mRNA degradation.Prospects of a novel vaccination strategy for human gamma-herpesviruses.Viral serine/threonine protein kinasesEvasion and subversion of interferon-mediated antiviral immunity by Kaposi's sarcoma-associated herpesvirus: an overview.Activation and regulation of interferon-β in immune responses.Potential of protein kinase inhibitors for treating herpesvirus-associated disease.
P2860
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P2860
Conserved herpesviral kinase promotes viral persistence by inhibiting the IRF-3-mediated type I interferon response.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Conserved herpesviral kinase p ...... ed type I interferon response.
@en
type
label
Conserved herpesviral kinase p ...... ed type I interferon response.
@en
prefLabel
Conserved herpesviral kinase p ...... ed type I interferon response.
@en
P2093
P2860
P1433
P1476
Conserved herpesviral kinase p ...... ed type I interferon response.
@en
P2093
Ann N Park
David Jesse Sanchez
Emilio Flano
Kyeong Seon Kim
Leming M Tong
Moon Jung Song
Ryan M O'Connell
Seungmin Hwang
Ting-Ting Wu
P2860
P304
P356
10.1016/J.CHOM.2008.12.013
P577
2009-02-01T00:00:00Z