Non-equivalent ligand selectivity of agonist sites in (α4β2)2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy.
about
Ion channels gated by acetylcholine and serotonin: structures, biology, and drug discoveryTargeting α4β2 nicotinic acetylcholine receptors in central nervous system disorders: perspectives on positive allosteric modulation as a therapeutic approach.An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors.Desformylflustrabromine (dFBr) and [3H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor.The Direct Actions of GABA, 2'-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABAA Receptors: Evidence for Receptors with Different Subunit Stoichiometries.Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State.Differential α4(+)/(-)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms.α4β2 Nicotinic Acetylcholine Receptors: RELATIONSHIPS BETWEEN SUBUNIT STOICHIOMETRY AND FUNCTION AT THE SINGLE CHANNEL LEVEL.Orthosteric and allosteric potentiation of heteromeric neuronal nicotinic acetylcholine receptors.Concatenated nicotinic acetylcholine receptors: A gift or a curse?Loops D, E and G in the Drosophila Dα1 subunit contribute to high neonicotinoid sensitivity of Dα1-chicken β2 nicotinic acetylcholine receptor.LY2087101 and dFBr share transmembrane binding sites in the (α4)3(β2)2 Nicotinic Acetylcholine Receptor.Role of the Cys Loop and Transmembrane Domain in the Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors.The fifth subunit of the (α4β2)2 β2 nicotinic ACh receptor modulates maximal ACh responses.Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2)2-type nicotinic acetylcholine receptor responses.Isoform-specific mechanisms of α3β4*-nicotinic acetylcholine receptor modulation by the prototoxin lynx1.
P2860
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P2860
Non-equivalent ligand selectivity of agonist sites in (α4β2)2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Non-equivalent ligand selectiv ...... terminant of agonist efficacy.
@en
type
label
Non-equivalent ligand selectiv ...... terminant of agonist efficacy.
@en
prefLabel
Non-equivalent ligand selectiv ...... terminant of agonist efficacy.
@en
P2093
P2860
P50
P356
P1476
Non-equivalent ligand selectiv ...... terminant of agonist efficacy.
@en
P2093
Constanza Alcaino
Federica Gasparri
Karina New
Manuel Faundez
Patricio Iturriaga Vasquez
P2860
P304
21795-21806
P356
10.1074/JBC.M114.555136
P407
P577
2014-06-16T00:00:00Z