Kinesin moves by an asymmetric hand-over-hand mechanism.
about
The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds.Direct observation of base-pair stepping by RNA polymeraseMechanistic analysis of the mitotic kinesin Eg5.Artificial Molecular MachinesAre coiled-coils of dimeric kinesins unwound during their walking on microtubule?The origin of minus-end directionality and mechanochemistry of Ncd motorsKar3Vik1, a member of the kinesin-14 superfamily, shows a novel kinesin microtubule binding pattern.The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement.Kar3 interaction with Cik1 alters motor structure and functionKinesin, 30 years later: Recent insights from structural studiesKinesin I transports tetramerized Kv3 channels through the axon initial segment via direct bindingBiophysical highlights from 54 years of macromolecular crystallographyEffects of surface passivation on gliding motility assaysThe forward and backward stepping processes of kinesin are gated by ATP bindingKinesin-5 allosteric inhibitors uncouple the dynamics of nucleotide, microtubule, and neck-linker binding sites.FRET measurements of kinesin neck orientation reveal a structural basis for processivity and asymmetry.Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.High-resolution optical tweezers for single-molecule manipulation.Optical trapping, driving, and arrangement of particles using a tapered fibre probe.Function and mechanism of axonal targeting of voltage-sensitive potassium channels.Direct physical study of kinetochore-microtubule interactions by reconstitution and interrogation with an optical force clamp.Processive movement of single kinesins on crowded microtubules visualized using quantum dots.Analysis of nematode mechanics by piezoresistive displacement clamp.Two distinct modes of processive kinesin movement in mixtures of ATP and AMP-PNP.Transport of beads by several kinesin motorsThe mitotic kinesin CENP-E is a processive transport motor.Precision steering of an optical trap by electro-optic deflection.Processive movement by a kinesin heterodimer with an inactivating mutation in one head.Kinesin's cover-neck bundle folds forward to generate forceDirect measurements of kinesin torsional properties reveal flexible domains and occasional stalk reversals during stepping.Direct observation of the binding state of the kinesin head to the microtubule.High-resolution, single-molecule measurements of biomolecular motion.Interlaced optical force-fluorescence measurements for single molecule biophysics.An integrated fiber-optic microfluidic device for detection of muscular force generation of microscopic nematodes.Ankyrin-G directly binds to kinesin-1 to transport voltage-gated Na+ channels into axons.Cytoplasmic dynein moves through uncoordinated stepping of the AAA+ ring domainsKinesin processivity is gated by phosphate releaseCamera-based three-dimensional real-time particle tracking at kHz rates and Ångström accuracyRapid double 8-nm steps by a kinesin mutant.Biased binding of single molecules and continuous movement of multiple molecules of truncated single-headed kinesin.
P2860
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P2860
Kinesin moves by an asymmetric hand-over-hand mechanism.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Kinesin moves by an asymmetric hand-over-hand mechanism.
@en
type
label
Kinesin moves by an asymmetric hand-over-hand mechanism.
@en
prefLabel
Kinesin moves by an asymmetric hand-over-hand mechanism.
@en
P2860
P356
P1433
P1476
Kinesin moves by an asymmetric hand-over-hand mechanism.
@en
P2093
Adrian N Fehr
Charles L Asbury
P2860
P304
P356
10.1126/SCIENCE.1092985
P407
P577
2003-12-04T00:00:00Z