about
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and micePlasma fibronectin supports hemostasis and regulates thrombosisVitronectin stabilizes thrombi and vessel occlusion but plays a dual role in platelet aggregation.Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin.Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo.A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy.Intravenous immunoglobulin inhibits anti-glycoprotein IIb-induced platelet apoptosis in a murine model of immune thrombocytopenia.Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GPIIbIIIa versus GPIbalpha antibodies.Fc-independent phagocytosis: implications for intravenous IgG therapy in immune thrombocytopenia.A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell-mediated responses that are differentially sensitive to therapy.Plasma fibronectin depletion enhances platelet aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor.Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy.Platelet antibodies and fetal growth: maternal antibodies against fetal platelet antigen 1a are strongly associated with reduced birthweight in boys.The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies.Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIbα antibodies.Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model.Decreased indoleamine 2,3-dioxygenase expression in dendritic cells and role of indoleamine 2,3-dioxygenase-expressing dendritic cells in immune thrombocytopenia.Thymic retention of CD4+CD25+FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia.Towards a prophylactic treatment of HPA-related foetal and neonatal alloimmune thrombocytopenia.Crosstalk between Platelets and the Immune System: Old Systems with New DiscoveriesFc-independent phagocytosis: implications for IVIG and other therapies in immune-mediated thrombocytopenia.Co-stimulation with LPS or Poly I:C markedly enhances the anti-platelet immune response and severity of fetal and neonatal alloimmune thrombocytopenia.Allogeneic platelet transfusions prevent murine T-cell-mediated immune thrombocytopenia.Association of autoantibody specificity and response to intravenous immunoglobulin G therapy in immune thrombocytopenia: a multicenter cohort study.Successful treatment with oseltamivir phosphate in a patient with chronic immune thrombocytopenia positive for anti-GPIb/IX autoantibody.Low-dose decitabine promotes megakaryocyte maturation and platelet production in healthy controls and immune thrombocytopenia.Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage.[Study on the relationship of platelet specific-autoantibodies with therapeutic outcomes by dexamethasone in immune thrombocytopenia purpura].[Correlation of the Desialylation of Platelets with Efficacy of the First-line Therapy for ITP].CD8+ T cells are predominantly protective and required for effective steroid therapy in murine models of immune thrombocytopenia.Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia[Influence of Anticoagulants on Detection of ITP Platelet-Specific Autoantibodies and Relationship of Autoantibody Types with Glucocorticoid Efficacy].CD20+ B-cell depletion therapy suppresses murine CD8+ T-cell-mediated immune thrombocytopenia.Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond.CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia.Abnormal hemostasis in a knock-in mouse carrying a variant of factor IX with impaired binding to collagen type IV.Plant food delphinidin-3-glucoside significantly inhibits platelet activation and thrombosis: novel protective roles against cardiovascular diseases.Platelets in hemostasis and thrombosis: role of integrins and their ligands.The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice.Glucagon-Like Peptide 1 Receptor Activation Attenuates Platelet Aggregation and Thrombosis.
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հետազոտող
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P106
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7102619243
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0000-0002-7621-2945