about
Sin3b interacts with Myc and decreases Myc levelsExome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinomaA small-cell lung cancer genome with complex signatures of tobacco exposureMutational processes molding the genomes of 21 breast cancersA comprehensive catalogue of somatic mutations from a human cancer genomeMassive genomic rearrangement acquired in a single catastrophic event during cancer developmentComplex landscapes of somatic rearrangement in human breast cancer genomes.Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cellsSomatic SF3B1 mutation in myelodysplasia with ring sideroblastsA genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion SequencingLeukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesisDevelopment of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolutionThe landscape of cancer genes and mutational processes in breast cancerThe life history of 21 breast cancersThe patterns and dynamics of genomic instability in metastatic pancreatic cancerSomatic structural rearrangements in genetically engineered mouse mammary tumors.An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.Spatial and temporal diversity in genomic instability processes defines lung cancer evolution.CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions.A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.Colorectal adenomas contain multiple somatic mutations that do not coincide with synchronous adenocarcinoma specimensRecurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution.Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencingNuclear envelope defects cause stem cell dysfunction in premature-aging miceCharacterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocolDevelopment and validation of a comprehensive genomic diagnostic tool for myeloid malignancies.Detailed molecular characterisation of acute myeloid leukaemia with a normal karyotype using targeted DNA capture.A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis.Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency.Whole exome sequencing of adenoid cystic carcinoma.Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.A Truncated Variant of ASCC1, a Novel Inhibitor of NF-κB, Is Associated with Disease Severity in Patients with Rheumatoid Arthritis.The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.Individualized strategies to target specific mechanisms of disease in malignant melanoma patients displaying unique mutational signaturesPLCG1 mutations in cutaneous T-cell lymphomas.
P50
Q24299671-7A4AA704-8C2B-4B50-B7B4-C4B20640B720Q24337664-3A7B1D2E-AA87-453D-AEBE-552660859FEFQ24600510-27E1C336-B744-4537-AE8B-599F03E67015Q24620915-33BF928F-9A5A-4D0B-A914-C52E075BD185Q24628532-18DECA86-E8C0-44A8-AB06-F983F0B2C2E4Q24631164-6501C61A-4DBD-4FD4-85AB-35D1EE44FF52Q24631412-999F028A-61BD-4ED8-9FB5-4D14F18D8C21Q24634829-30F4C81C-855D-4D85-82B3-BF893F41864FQ27851675-E8E234B0-C73A-44B0-93D6-430CBE7BD93AQ27852431-22043585-6E0B-4176-90F9-1F4BF81DAD09Q27860948-F197822F-0A8E-4152-9095-3D620E3677D8Q28386212-6B7DB806-859E-4C31-A3A3-B635F4F1258FQ28655705-57AEC5F1-15A0-456B-992B-DFD00330EA6AQ29614637-1ABE73FC-79BC-417E-9752-740250351E18Q29614642-FD78185D-4AD4-4A3C-B6E4-7BFC8F476D60Q29618121-634B9708-5411-42B9-BAA7-D657C6DA6195Q30472845-AAFA3AF0-FB08-43DB-A741-2F833D35AEDAQ30581758-FA13EC87-62AD-4D07-865D-1564F797825CQ34440150-F3BF89F4-88B9-41EC-B793-7C7AB127E373Q34442770-68C28AA3-7A56-4FE6-86EE-3736BDFDC692Q34499647-7A505505-B8EB-43B9-BC92-C8D21428ACD4Q34585248-D5AD83E9-F838-4687-841F-20365732D119Q34729793-B4800C0E-4383-4F4C-9151-C152605EB980Q34790173-DD22DF44-466C-4DD7-ADEF-F7CC12E5C898Q35180651-A5835852-11CA-4623-9293-C5A11291BA67Q35247152-CD498039-ECED-46DC-89B5-828D5EC10E17Q36256943-44E32FA3-CC31-438A-9E4C-31785DE80B5CQ36527165-72270562-C81F-46C8-A1CC-DB0FD4E31837Q36715925-4CCCB6A9-9E5A-4C06-B45F-96935FF3A156Q37076434-F34259EB-93FC-48D7-8967-F08482AD1A13Q37158516-0EB6FD0D-875E-4F2D-95A9-6B5ED564EEEBQ37310984-B552C00E-9757-4269-9A96-13EC63E61ED9Q37338044-5611B0B8-5378-491C-A9FB-A95FAD5E3498Q37722072-9C92F10F-5262-45A2-9F14-8F59FFCA68DBQ38429500-B2103BED-DD07-4A18-B938-2E98C7C109E6Q38707232-96D4DD9B-8701-4144-A9CC-977383642B5FQ38824674-46C78C5E-40BC-46AA-A400-93AD38C29474Q38836796-563BF45C-5ABC-4E8D-BA4D-097E4EAA61C1Q38839023-E9F6BB2A-63D0-4D8E-B50B-15BCB3DEFDABQ39027098-27CB52A0-6459-4C36-ACE6-D388E81AAA82
P50
description
biologiste espagnol
@fr
biologo espainiarra
@eu
biologo spagnolo
@it
biòleg espanyol
@ca
biólogo espanhol
@pt
biólogo español
@es
biólogo, investigador e profesor español
@gl
biólogu español
@ast
researcher ORCID ID = 0000-0002-0969-506X
@en
name
Ignacio Varela Egocheaga
@gl
Ignacio Varela
@en
Ignacio Varela
@es
Ignacio Varela
@ga
Ignacio Varela
@nl
Ignacio Varela
@sl
type
label
Ignacio Varela Egocheaga
@gl
Ignacio Varela
@en
Ignacio Varela
@es
Ignacio Varela
@ga
Ignacio Varela
@nl
Ignacio Varela
@sl
prefLabel
Ignacio Varela Egocheaga
@gl
Ignacio Varela
@en
Ignacio Varela
@es
Ignacio Varela
@ga
Ignacio Varela
@nl
Ignacio Varela
@sl
P1053
G-1699-2016
P106
P19
P21
P27
P31
P3829
P496
0000-0002-0969-506X
P569
1981-03-26T00:00:00Z