about
Insulin receptor substrate-1 (IRS-1) forms a ribonucleoprotein complex associated with polysomesNovel repressor regulates insulin sensitivity through interaction with Foxo1The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsPhosphatidylinositol 3-Kinase-Associated Protein (PI3KAP)/XB130 Crosslinks Actin Filaments through Its Actin Binding and Multimerization Properties In Vitro and Enhances Endocytosis in HEK293 CellsHSP90 interacting with IRS-2 is involved in cAMP-dependent potentiation of IGF-I signals in FRTL-5 cellsInsulin receptor substrate-3 functions as transcriptional activator in the nucleusThe Inner Nuclear Membrane Protein Nemp1 Is a New Type of RanGTP-Binding Protein in EukaryotesAspp2 negatively regulates body growth but not developmental timing by modulating IRS signaling in zebrafish embryos.Constitutive expression of insulin receptor substrate (IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblastsThe Short-Stature Homeobox-Containing Gene (shox/SHOX) Is Required for the Regulation of Cell Proliferation and Bone Differentiation in Zebrafish Embryo and Human Mesenchymal Stem Cells.Paraquat-induced oxidative stress represses phosphatidylinositol 3-kinase activities leading to impaired glucose uptake in 3T3-L1 adipocytes.Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationTumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytesRNautophagy/DNautophagy possesses selectivity for RNA/DNA substratesPhosphatidylinositol 3-kinase (PI3K) activity bound to insulin-like growth factor-I (IGF-I) receptor, which is continuously sustained by IGF-I stimulation, is required for IGF-I-induced cell proliferation.Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent modelIGFBP-5 induces epithelial and fibroblast responses consistent with the fibrotic response.Insulin receptor substrate-1 associates with small nucleolar RNA which contributes to ribosome biogenesis.Familial short stature with IGF-I receptor gene anomaly.Rapid increase in fibroblast growth factor 21 in protein malnutrition and its impact on growth and lipid metabolism.Roles of chondroitin sulfate proteoglycan 4 in fibrogenic/adipogenic differentiation in skeletal muscle tissues.Chapter Seven - When Phosphorylation Encounters Ubiquitination: A Balanced Perspective on IGF-1R Signaling.Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.Insulin injection restored increased insulin receptor substrate (IRS)-2 protein during short-term protein restriction but did not affect reduced insulin-like growth factor (IGF)-I mRNA or increased triglyceride accumulation in the liver of rats.Steroid hormones are novel nucleoside transport inhibitors by competition with nucleosides for their transporters.A novel IRS-1-associated protein, DGKζ regulates GLUT4 translocation in 3T3-L1 adipocytes.Thyroglobulin (Tg) activates MAPK pathway to induce thyroid cell growth in the absence of TSH, insulin and serum.Novel missense mutation in the IGF-I receptor L2 domain results in intrauterine and postnatal growth retardation.KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells.Distinct modes of activation of phosphatidylinositol 3-kinase in response to cyclic adenosine 3', 5'-monophosphate or insulin-like growth factor I play different roles in regulation of cyclin D1 and p27Kip1 in FRTL-5 cells.Runx1 promotes angiogenesis by downregulation of insulin-like growth factor-binding protein-3.Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase.The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation.Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression.New approach for the establishment of an hepatocyte cell line derived from rat early embryonic stem cells.Long-term hormonal regulation of the cAMP-specific phosphodiesterases in cultured FRTL-5 thyroid cells.Amino acid regulation of gene transcription of rat insulin-like growth factor-binding protein-1.In vivo regulation of glycogen synthase kinase 3β activity in neurons and brainsProlyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunitBranched-chain amino acid supplementation restores reduced insulinotropic activity of a low-protein diet through the vagus nerve in rats.
P50
Q24295119-F8AABC4D-4283-4CAB-BBAC-97E8025BB2ABQ24314731-9C7278BD-C9B4-46F2-870D-02254A971908Q28088661-D0DEFEC9-F06C-4B5D-82E8-AC2FDDD4E773Q28383770-775F5316-A863-497D-A74A-8151987656F4Q28574031-B3094C02-CB0E-431C-B6C5-6F11B0438F35Q28574967-F43D5427-0819-4C1E-AE5C-C58227F76C5CQ28589245-BE27E528-39C2-4C71-8B86-123DF415E57EQ30009509-EF7FDE77-3394-4565-A17A-B28377254F61Q31032454-A849806C-EFEB-4D6D-8550-C1EB61390332Q33774631-0A4B20EC-8032-44ED-A64E-D131303FA468Q33967046-DD941CF3-E8FB-4D6E-954B-3041B58A5EE0Q34387886-97EBC446-E954-4A8C-AD6F-6B09E2CAAADDQ35126720-905A9C61-428E-4223-8EAA-FBD541BFD0EFQ35885928-46CF1F5F-0AE1-4E02-B546-7068A7312717Q36215994-77EC2312-995E-4535-AB82-B638A1600F9CQ36492869-692990DC-7614-46AE-A8C2-9DED78676F77Q37554650-7952F34B-7AF1-49B1-83FE-52310481FF1BQ37615800-6577D93B-A0F5-4CC4-8005-E7BF66005861Q37947003-405A89A1-1C91-473C-B9A4-826C822E1D75Q38296688-3EEB181C-60F6-4C38-95D4-77A6E44A15D4Q38748766-07E6261C-E61F-43B3-9E38-DF7D1CA98531Q38886242-ED1B39EF-135D-41F1-95E6-0B0C1257CF5EQ38886538-95D1FCF8-AD13-4F0C-B93E-B666AC99C02CQ38974337-DF2D53D1-B964-4399-BE52-2382AF430014Q39043933-C5C4C7A4-BAE7-4FFF-B12D-425972F8CD6CQ39292601-8C1777DE-42A1-4B0D-8468-EFEAF3F0CCA1Q39374518-C1F0689B-DD10-4BC9-9185-5C63DA460E6DQ39400999-CCDBE3E4-51B6-43BA-87DD-F9C7362A6450Q39557993-B2973500-EB6F-44D7-A763-F117E76B91FCQ39993169-B952F9C7-E209-41DE-B439-DA5DDE856157Q40481703-26583ADB-0C3E-4F11-B8C0-AE6E4F21FF03Q40484050-2A9AFBED-185E-4650-AA5F-93DADC2D5EBFQ40521731-037503C1-EE84-4250-AA79-F6546AD87740Q40582971-0C0A5FD6-8EE4-43C3-863B-F0E2B10EF076Q40634942-C45CA9C5-ED0E-42AC-BD5C-3278195368E8Q40789701-8CF973AD-2584-42AE-BFB4-0A5E25958D73Q40897461-208D83DF-073F-439C-ACDB-3C905D4B701AQ41447595-663B9E4E-EBBF-470A-A1F5-E25CFBA1F77AQ41456327-46864491-EE08-4957-B863-F3D144588528Q41716671-20A0ACCC-9927-461B-9B1C-C0FBC7090D1C
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Shin-Ichiro Takahashi
@ast
Shin-Ichiro Takahashi
@en
Shin-Ichiro Takahashi
@es
Shin-Ichiro Takahashi
@nl
Shin-Ichiro Takahashi
@sl
type
label
Shin-Ichiro Takahashi
@ast
Shin-Ichiro Takahashi
@en
Shin-Ichiro Takahashi
@es
Shin-Ichiro Takahashi
@nl
Shin-Ichiro Takahashi
@sl
prefLabel
Shin-Ichiro Takahashi
@ast
Shin-Ichiro Takahashi
@en
Shin-Ichiro Takahashi
@es
Shin-Ichiro Takahashi
@nl
Shin-Ichiro Takahashi
@sl
P214
P106
P214
P31
P496
0000-0002-2323-2010
P7859
lccn-n98012285