Extended treatment with selective phosphatidylinositol 3-kinase and mTOR inhibitors has effects on metabolism, growth, behaviour and bone strength.
about
IL-6 and IGF-1 Signaling Within and Between Muscle and Bone: How Important is the mTOR Pathway for Bone Metabolism?PI3Kα inhibition reduces obesity in miceA preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors.Dactolisib (NVP-BEZ235) toxicity in murine brain tumour models.Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers: Preclinical Discovery to Phase I Trial Evaluation.Structure, function and inhibition of the phosphoinositide 3-kinase p110α enzyme.Outlook on PI3K/AKT/mTOR inhibition in acute leukemia.Inhibition of class IA PI3K enzymes in non-small cell lung cancer cells uncovers functional compensation among isoforms.The effect of the dual PI3K and mTOR inhibitor BEZ235 on tumour growth and osteolytic bone disease in multiple myeloma.Class I PI-3-Kinase Signaling Is Critical for Bone Formation Through Regulation of SMAD1 Activity in Osteoblasts.Mechanical Stimulation and IGF-1 Enhance mRNA Translation Rate in Osteoblasts Via Activation of the AKT-mTOR Pathway.
P2860
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P2860
Extended treatment with selective phosphatidylinositol 3-kinase and mTOR inhibitors has effects on metabolism, growth, behaviour and bone strength.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Extended treatment with select ...... , behaviour and bone strength.
@en
Extended treatment with select ...... , behaviour and bone strength.
@nl
type
label
Extended treatment with select ...... , behaviour and bone strength.
@en
Extended treatment with select ...... , behaviour and bone strength.
@nl
prefLabel
Extended treatment with select ...... , behaviour and bone strength.
@en
Extended treatment with select ...... , behaviour and bone strength.
@nl
P2093
P2860
P356
P1433
P1476
Extended treatment with select ...... , behaviour and bone strength.
@en
P2093
Andrew Grey
Gordon W Rewcastle
Greg C Smith
Greg D Gamble
Jessica L Costa
Jillian Cornish
Maureen Watson
Michelle Dickinson
Peter R Shepherd
Sophie Leung
P2860
P304
P356
10.1111/FEBS.12428
P407
P577
2013-08-12T00:00:00Z