The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.
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Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathyIRS-4 mediates protein kinase B signaling during insulin stimulation without promoting antiapoptosisDistinct signal transduction processes by IL-4 and IL-13 and influences from the Q551R variant of the human IL-4 receptor alpha chainInsulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycleThe forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growthInteraction between Brk kinase and insulin receptor substrate-4.Fyn tyrosine kinase regulates oligodendroglial cell development but is not required for morphological differentiation of oligodendrocytes.Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.From preadipocyte to adipocyte: differentiation-directed signals of insulin from the cell surface to the nucleus.Targeting insulin-like growth factor-I and insulin-like growth factor-binding protein-3 signaling pathways. A novel therapeutic approach for asthmaHyperadiponectinemia enhances bone formation in mice.Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolismAltered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential.Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity.Role of pescadillo and upstream binding factor in the proliferation and differentiation of murine myeloid cells.Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes.Insulin receptor substrate-2 maintains predominance of anabolic function over catabolic function of osteoblasts.The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2.Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover.Progesterone receptor-B regulation of insulin-like growth factor-stimulated cell migration in breast cancer cells via insulin receptor substrate-2.Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2.Insulin receptor substrate 3 (IRS-3) and IRS-4 impair IRS-1- and IRS-2-mediated signaling.Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.Modulated expression of the epidermal growth factor-like homeotic protein dlk influences stromal-cell-pre-B-cell interactions, stromal cell adipogenesis, and pre-B-cell interleukin-7 requirements.The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulinMolecular mechanism of insulin-induced degradation of insulin receptor substrate 1Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling.Cellular growth inhibition by TGF-beta1 involves IRS proteins.Signalling pathways of insulin-like growth factor-I that are augmented by cAMP in FRTL-5 cells.Regulation of gene expression, growth, and cell survival by IL-4: contribution of multiple signaling pathways.Insulin receptor substrate 1 expression enhances the sensitivity of 32D cells to chemotherapy-induced cell death.IRS-1 tyrosine phosphorylation reflects insulin-induced metabolic and mitogenic responses in 3T3-L1 pre-adipocytes.The effect of glucose concentration on insulin-induced 3T3-L1 adipose cell differentiation.Targeting Adrenomedullin to Improve Lipid Homeostasis in Diabetic Pregnancies.IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View.
P2860
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P2860
The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The IRS-2 gene on murine chrom ...... r insulin and cytokine action.
@en
The IRS-2 gene on murine chrom ...... r insulin and cytokine action.
@nl
type
label
The IRS-2 gene on murine chrom ...... r insulin and cytokine action.
@en
The IRS-2 gene on murine chrom ...... r insulin and cytokine action.
@nl
prefLabel
The IRS-2 gene on murine chrom ...... r insulin and cytokine action.
@en
The IRS-2 gene on murine chrom ...... r insulin and cytokine action.
@nl
P2093
P356
P1476
The IRS-2 gene on murine chrom ...... or insulin and cytokine action
@en
P2093
Copeland NG
Glasheen E
Jenkins NA
Myers MG Jr
P304
P356
10.1210/MEND.11.2.9885
P577
1997-02-01T00:00:00Z