Catalytic mechanism of the glutathione peroxidase-type tryparedoxin peroxidase of Trypanosoma brucei.
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Structural and mechanistic insights into type II trypanosomatid tryparedoxin-dependent peroxidasesStructural Basis for a Distinct Catalytic Mechanism in Trypanosoma brucei Tryparedoxin PeroxidaseStructural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I)Backbone NMR assignments of tryparedoxin, the central protein in the hydroperoxide detoxification cascade of African trypanosomes, in the oxidized and reduced form.Roles of trypanothione S-transferase and tryparedoxin peroxidase in resistance to antimonialsThe Corynebacterium glutamicum mycothiol peroxidase is a reactive oxygen species-scavenging enzyme that shows promiscuity in thiol redox control.Antitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism.A comparative study of type I and type II tryparedoxin peroxidases in Leishmania major.High throughput screening against the peroxidase cascade of African trypanosomes identifies antiparasitic compounds that inactivate tryparedoxin.The dithiol glutaredoxins of african trypanosomes have distinct roles and are closely linked to the unique trypanothione metabolism.ATP-dependent ligases in trypanothione biosynthesis--kinetics of catalysis and inhibition by phosphinic acid pseudopeptides.The conserved Cys76 plays a crucial role for the conformation of reduced glutathione peroxidase-type tryparedoxin peroxidase.The thioreduction component CcmG confers efficiency and the heme ligation component CcmH ensures stereo-specificity during cytochrome c maturation.Hydroperoxide and peroxynitrite reductase activity of poplar thioredoxin-dependent glutathione peroxidase 5: kinetics, catalytic mechanism and oxidative inactivationThiol Peroxidases of Trypanosomatids
P2860
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P2860
Catalytic mechanism of the glutathione peroxidase-type tryparedoxin peroxidase of Trypanosoma brucei.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
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2007年學術文章
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2007年學術文章
@zh-hant
name
Catalytic mechanism of the glu ...... oxidase of Trypanosoma brucei.
@en
Catalytic mechanism of the glu ...... oxidase of Trypanosoma brucei.
@nl
type
label
Catalytic mechanism of the glu ...... oxidase of Trypanosoma brucei.
@en
Catalytic mechanism of the glu ...... oxidase of Trypanosoma brucei.
@nl
prefLabel
Catalytic mechanism of the glu ...... oxidase of Trypanosoma brucei.
@en
Catalytic mechanism of the glu ...... oxidase of Trypanosoma brucei.
@nl
P2093
P2860
P356
P1433
P1476
Catalytic mechanism of the glu ...... oxidase of Trypanosoma brucei.
@en
P2093
Johannes Melchers
Marcelo A Comini
R Luise Krauth-Siegel
Tanja Schlecker
Thomas Ruppert
P2860
P304
P356
10.1042/BJ20070259
P407
P577
2007-08-01T00:00:00Z