Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair.
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Structural Basis for Bulky-Adduct DNA-Lesion Recognition by the Nucleotide Excision Repair Protein Rad14Ribonucleotides as nucleotide excision repair substrates.Nucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactionsDifferential nucleotide excision repair susceptibility of bulky DNA adducts in different sequence contexts: hierarchies of recognition signalsHuman genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo[a]pyreneDistant neighbor base sequence context effects in human nucleotide excision repair of a benzo[a]pyrene-derived DNA lesion.Base sequence context effects on nucleotide excision repair.Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions.Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitroAdenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are notInfluence of flanking sequence context on the conformational flexibility of aminofluorene-modified dG adduct in dA mismatch DNA duplexes.The sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisionsChemistry and structural biology of DNA damage and biological consequencesC8-linked bulky guanosine DNA adducts: experimental and computational insights into adduct conformational preferences and resulting mutagenicity.Adenine versus guanine DNA adducts of aristolochic acids: role of the carcinogen-purine linkage in the differential global genomic repair propensity.Repair-Resistant DNA Lesions.Enthalpy-entropy contribution to carcinogen-induced DNA conformational heterogeneityEnhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex.BPDE-induced genotoxicity: relationship between DNA adducts, mutagenicity in the in vitro PIG-A assay, and the transcriptional response to DNA damage in TK6 cells.Single-stranded DNA Binding by the Helix-Hairpin-Helix Domain of XPF Protein Contributes to the Substrate Specificity of the ERCC1-XPF Protein Complex.Molecular dynamics of dibenz[a,h]anthracene and its metabolite interacting with lung surfactant phospholipid bilayers.
P2860
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P2860
Dynamics of a benzo[a]pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts: enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide excision repair.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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name
Dynamics of a benzo[a]pyrene-d ...... to nucleotide excision repair.
@en
Dynamics of a benzo[a]pyrene-d ...... to nucleotide excision repair.
@nl
type
label
Dynamics of a benzo[a]pyrene-d ...... to nucleotide excision repair.
@en
Dynamics of a benzo[a]pyrene-d ...... to nucleotide excision repair.
@nl
prefLabel
Dynamics of a benzo[a]pyrene-d ...... to nucleotide excision repair.
@en
Dynamics of a benzo[a]pyrene-d ...... to nucleotide excision repair.
@nl
P2093
P2860
P1476
Dynamics of a benzo[a]pyrene-d ...... to nucleotide excision repair.
@en
P2093
Dinshaw J Patel
Nicholas E Geacintov
Suse Broyde
P2860
P304
P356
10.1016/J.JMB.2007.09.034
P407
P577
2007-09-19T00:00:00Z