IgM rheumatoid factor amplifies the inflammatory response of macrophages induced by the rheumatoid arthritis-specific immune complexes containing anticitrullinated protein antibodies.
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Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.Anti-Hinge Antibodies Recognize IgG Subclass- and Protease-Restricted Neoepitopes.In vitro eradication of citrullinated protein specific B-lymphocytes of rheumatoid arthritis patients by targeted bifunctional nanoparticles.Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis.Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis.Anti-citrullinated protein antibodies and high levels of rheumatoid factor are associated with systemic bone loss in patients with early untreated rheumatoid arthritis.Mechanisms involved in triggering rheumatoid arthritis.Arthritis models: usefulness and interpretation.Among human macrophages polarised to different phenotypes, the M-CSF-oriented cells present the highest pro-inflammatory response to the rheumatoid arthritis-specific immune complexes containing ACPA.Autoantibodies to human citrullinated fibrinogen and their subfamilies to the α36-50Cit and β60-74Cit fibrin peptides similarly predict radiographic damages: a prospective study in the French ESPOIR cohort of very early arthritides.Identification of human IgG1 variant with enhanced FcRn binding and without increased binding to rheumatoid factor autoantibody.High titers of both rheumatoid factor and anti-CCP antibodies at baseline in patients with rheumatoid arthritis are associated with increased circulating baseline TNF level, low drug levels, and reduced clinical responses: a post hoc analysis of theIncreased inflammation and disease activity among current cigarette smokers with rheumatoid arthritis: a cross-sectional analysis of US veterans.Analysis of serum immune markers in seropositive and seronegative rheumatoid arthritis and in high-risk seropositive arthralgia patients.Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation.Identification of IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis in a Genome-Wide Association Study.The role of anti-citrullinated protein antibodies (ACPA) in the pathogenesis of rheumatoid arthritis.Conversion to seronegative status after abatacept treatment in patients with early and poor prognostic rheumatoid arthritis is associated with better radiographic outcomes and sustained remission: post hoc analysis of the AGREE study.Rituximab hypersensitivity in IgG4-related disease: successful desensitization in a patient with IgG4 rheumatoid factor.IgG Subclass Specificity Discriminates Restricted IgM Rheumatoid Factor Responses From More Mature Anti-Citrullinated Protein Antibody-Associated or Isotype-Switched IgA Responses
P2860
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P2860
IgM rheumatoid factor amplifies the inflammatory response of macrophages induced by the rheumatoid arthritis-specific immune complexes containing anticitrullinated protein antibodies.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
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2014年學術文章
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name
IgM rheumatoid factor amplifie ...... rullinated protein antibodies.
@en
IgM rheumatoid factor amplifie ...... rullinated protein antibodies.
@nl
type
label
IgM rheumatoid factor amplifie ...... rullinated protein antibodies.
@en
IgM rheumatoid factor amplifie ...... rullinated protein antibodies.
@nl
prefLabel
IgM rheumatoid factor amplifie ...... rullinated protein antibodies.
@en
IgM rheumatoid factor amplifie ...... rullinated protein antibodies.
@nl
P2093
P2860
P1476
IgM rheumatoid factor amplifie ...... trullinated protein antibodies
@en
P2093
Cyril Clavel
Géraldine Offer
Jean-Louis Pasquali
Lætitia Laurent
Mireille Sebbag
Ndiémé Ndongo-Thiam
Pierre Miossec
P2860
P304
P356
10.1136/ANNRHEUMDIS-2013-204543
P407
P577
2014-03-11T00:00:00Z