Validation of a biotherapeutic immunoaffinity-LC-MS/MS assay in monkey serum: 'plug-and-play' across seven molecules.

about

Do we have a mature LC-MS/MS methodology for therapeutic monoclonal antibody bioanalysis?Novel strategy using tryptic peptide immunoaffinity-based LC-MS/MS to quantify denosumab in monkey serum.Immunoaffinity MS: adding increased value through hybrid methods.

P2860

Q45067256-9E549603-8C7F-48FA-A980-E985FE2ABAAB Q47748470-61E24457-FCA6-4555-A151-C061781DE824 Q51389787-398D2AC5-2C3A-440D-B394-E4ADF6392D05

P2860

Validation of a biotherapeutic immunoaffinity-LC-MS/MS assay in monkey serum: 'plug-and-play' across seven molecules.

Item

http://www.wikidata.org/entity/Q45037829

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年学术文章

@wuu

2016年学术文章

@zh

2016年学术文章

@zh-cn

2016年学术文章

@zh-hans

2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

@yue

2016年學術文章

@zh-hant

name

Validation of a biotherapeutic ...... -play' across seven molecules.

@en

Validation of a biotherapeutic ...... -play' across seven molecules.

@nl

type

Item

label

Validation of a biotherapeutic ...... -play' across seven molecules.

@en

Validation of a biotherapeutic ...... -play' across seven molecules.

@nl

prefLabel

Validation of a biotherapeutic ...... -play' across seven molecules.

@en

Validation of a biotherapeutic ...... -play' across seven molecules.

@nl

P1476

Validation of a biotherapeutic ...... -play' across seven molecules.

@en

P2093

Diego F Cortes

http://www.w3.org/2001/XMLSchema#string

Junlong Shao

http://www.w3.org/2001/XMLSchema#string

Keyang Xu

http://www.w3.org/2001/XMLSchema#string

Luna Liu

http://www.w3.org/2001/XMLSchema#string

Rand Jenkins

http://www.w3.org/2001/XMLSchema#string

Surinder Kaur

http://www.w3.org/2001/XMLSchema#string

William R Mylott

http://www.w3.org/2001/XMLSchema#string

P2860

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

Ligand-binding mass spectrometry to study biotransformation of fusion protein drugs and guide immunoassay development: strategic approach and application to peptibodies targeting the thrombopoietin receptor.

Quality requirements for critical assay reagents used in bioanalysis of therapeutic proteins: what bioanalysts should know about their reagents.

Development of a validated liquid chromatography tandem mass spectrometry assay for a PEGylated adnectin in cynomolgus monkey plasma using protein precipitation and trypsin digestion.

Differentiation and quantification of endogenous and recombinant-methionyl human leptin in clinical plasma samples by immunocapture/mass spectrometry.

Recommendations for validation of LC-MS/MS bioanalytical methods for protein biotherapeutics.

Fully validated LC-MS/MS assay for the simultaneous quantitation of coadministered therapeutic antibodies in cynomolgus monkey serum.

General LC-MS/MS method approach to quantify therapeutic monoclonal antibodies using a common whole antibody internal standard with application to preclinical studies.

In vivo deamidation characterization of monoclonal antibody by LC/MS/MS.

A multiplexed hybrid LC-MS/MS pharmacokinetic assay to measure two co-administered monoclonal antibodies in a clinical study.

P304

1565-1577

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4155/BIO-2016-0117

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2016-07-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27396481

http://www.w3.org/2001/XMLSchema#string

Validation of a biotherapeutic immunoaffinity-LC-MS/MS assay in monkey serum: 'plug-and-play' across seven molecules.

about

P2860

P2860

Validation of a biotherapeutic immunoaffinity-LC-MS/MS assay in monkey serum: 'plug-and-play' across seven molecules.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698