Genetic retargeting of adenovirus vectors: functionality of targeting ligands and their influence on virus viability.
about
Cell entry and trafficking of human adenovirus bound to blood factor X is determined by the fiber serotype and not hexon:heparan sulfate interactionProtein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysisA strategy for adenovirus vector targeting with a secreted single chain antibody.Peptide-based technologies to alter adenoviral vector tropism: ways and means for systemic treatment of cancerHer2-specific multivalent adapters confer designed tropism to adenovirus for gene targetingChemoselective attachment of small molecule effector functionality to human adenoviruses facilitates gene delivery to cancer cells.Development of a targeted gene vector platform based on simian adenovirus serotype 24.Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridgeReduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and alphav integrin-binding ablation.Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation.Transductional targeting of adenovirus vectors for gene therapyMetabolic biotinylation of recombinant proteins in mammalian cells and in mice.Oncolytic adenoviruses - selective retargeting to tumor cells.Current advances and future challenges in Adenoviral vector biology and targetingRetargeted oncolytic adenovirus displaying a single variable domain of camelid heavy-chain-only antibody in a fiber protein.Improved adenovirus type 5 vector-mediated transduction of resistant cells by piggybacking on coxsackie B-adenovirus receptor-pseudotyped baculovirus.Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody.Tropism-modification strategies for targeted gene delivery using adenoviral vectors.Unnatural amino acid incorporation onto adenoviral (Ad) coat proteins facilitates chemoselective modification and retargeting of Ad type 5 vectors.Re-targeted adenovirus vectors with dual specificity; binding specificities conferred by two different Affibody molecules in the fiber.Adenovirus targeting to HLA-A1/MAGE-A1-positive tumor cells by fusing a single-chain T-cell receptor with minor capsid protein IX.Genetically targeted adenovirus vector directed to CD40-expressing cellsFormation of polyomavirus-like particles with different VP1 molecules that bind the urokinase plasminogen activator receptor.Modification of adenovirus capsid with a designed protein ligand yields a gene vector targeted to a major molecular marker of cancer.Efficient incorporation of a functional hyper-stable single-chain antibody fragment protein-IX fusion in the adenovirus capsid.An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery.Tumor cell targeted gene delivery by adenovirus 5 vectors carrying knobless fibers with antibody-binding domains.Gene transduction and cell entry pathway of fiber-modified adenovirus type 5 vectors carrying novel endocytic peptide ligands selected on human tracheal glandular cells.Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IXChemoselective modification of viral surfaces via bioorthogonal click chemistry.The effect of fiber truncations on the stability of adenovirus type 5.The maturation of murine dendritic cells induced by human adenovirus is mediated by the fiber knob domain.Decreased immune reactivity towards a knobless, affibody-targeted adenovirus type 5 vector.Development of an adenovirus vector vaccine platform for targeting dendritic cells.Designer Oncolytic Adenovirus: Coming of Age.
P2860
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P2860
Genetic retargeting of adenovirus vectors: functionality of targeting ligands and their influence on virus viability.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Genetic retargeting of adenovi ...... influence on virus viability.
@en
Genetic retargeting of adenovi ...... influence on virus viability.
@nl
type
label
Genetic retargeting of adenovi ...... influence on virus viability.
@en
Genetic retargeting of adenovi ...... influence on virus viability.
@nl
prefLabel
Genetic retargeting of adenovi ...... influence on virus viability.
@en
Genetic retargeting of adenovi ...... influence on virus viability.
@nl
P2093
P2860
P356
P1476
Genetic retargeting of adenovi ...... influence on virus viability.
@en
P2093
Leif Lindholm
Maria K Magnusson
Petra Henning
Pierre Boulanger
Saw See Hong
P2860
P304
P356
10.1002/JGM.285
P577
2002-07-01T00:00:00Z