Urokinase activates macrophage PON2 gene transcription via the PI3K/ROS/MEK/SREBP-2 signalling cascade mediated by the PDGFR-beta.

Urokinase activates macrophage PON2 gene transcription via the PI3K/ROS/MEK/SREBP-2 signalling cascade mediated by the PDGFR-beta.

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http://www.wikidata.org/entity/Q45982085
The human paraoxonase gene cluster as a target in the treatment of atherosclerosisProtectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and CancerPON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell deathParaoxonase 2 decreases renal reactive oxygen species production, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of NADPH oxidaseDownregulation of uPAR and cathepsin B induces apoptosis via regulation of Bcl-2 and Bax and inhibition of the PI3K/Akt pathway in gliomas.Paraoxonase enzyme protects retinal pigment epithelium from chlorpyrifos insult.Modulation of paraoxonase 2 (PON2) in mouse brain by the polyphenol quercetin: a mechanism of neuroprotection?The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients.Paraoxonase-2 (PON2) in brain and its potential role in neuroprotection.Site-2 protease responds to oxidative stress and regulates oxidative injury in mammalian cells.Dynamics of PDGFRβ expression in different cell types after brain injury.Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells.Role of PDGF-D and PDGFR-β in neuroinflammation in experimental ICH mice model.Paraoxonases-1, -2 and -3: What are their functions?Acrolein increases macrophage atherogenicity in association with gut microbiota remodeling in atherosclerotic mice: protective role for the polyphenol-rich pomegranate juice.Human paraoxonase 2.
P2860

Urokinase activates macrophage PON2 gene transcription via the PI3K/ROS/MEK/SREBP-2 signalling cascade mediated by the PDGFR-beta.

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http://www.wikidata.org/entity/Q45982085
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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Urokinase activates macrophage ...... de mediated by the PDGFR-beta.
@en
Urokinase activates macrophage ...... de mediated by the PDGFR-beta.
@nl
type
label
Urokinase activates macrophage ...... de mediated by the PDGFR-beta.
@en
Urokinase activates macrophage ...... de mediated by the PDGFR-beta.
@nl
prefLabel
Urokinase activates macrophage ...... de mediated by the PDGFR-beta.
@en
Urokinase activates macrophage ...... de mediated by the PDGFR-beta.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Urokinase activates macrophage ...... ade mediated by the PDGFR-beta
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921