Nicotine self-administration in mice is associated with rates of nicotine inactivation by CYP2A5.
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Do initial responses to drugs predict future use or abuse?Predictors of the nicotine reinforcement threshold, compensation, and elasticity of demand in a rodent model of nicotine reduction policy.Developmental hippocampal neuroplasticity in a model of nicotine replacement therapy during pregnancy and breastfeedingSex differences in nicotine preference.Nine generations of selection for high and low nicotine intake in outbred Sprague-Dawley rats.Strain-dependent effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning.Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse modelEffects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in miceA novel CYP2A6 allele, CYP2A6*23, impairs enzyme function in vitro and in vivo and decreases smoking in a population of Black-African descentA novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo.Individual differences in oral nicotine intake in rats.The β3 subunit of the nicotinic acetylcholine receptor: Modulation of gene expression and nicotine consumption.Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathwayOral Nicotine Self-Administration in RodentsCorrelates of individual differences in compensatory nicotine self-administration in rats following a decrease in nicotine unit doseFirst demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo.Mechanism-based medication development for the treatment of nicotine dependence.Nicotine Increases Codeine Analgesia Through the Induction of Brain CYP2D and Central Activation of Codeine to Morphine.Sex differences in response to nicotine in C57Bl/6:129SvEv mice.Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse.Subjective responses to intravenous nicotine: greater sensitivity in women than in men.Pharmacokinetic and pharmacodynamics studies of nicotine after oral administration in mice: effects of methoxsalen, a CYP2A5/6 inhibitor.Novel CYP2A6 variants identified in African Americans are associated with slow nicotine metabolism in vitro and in vivo.Does coffee consumption impact on heaviness of smoking?Delivery of nicotine aerosol to mice via a modified electronic cigarette device.Effect of Brain CYP2B Inhibition on Brain Nicotine Levels and Nicotine Self-Administration.A convenient UHPLC-MS/MS method for routine monitoring of plasma and brain levels of nicotine and cotinine as a tool to validate newly developed preclinical smoking model in mouse.Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent.Nicotine metabolism and urinary elimination in mouse: in vitro and in vivo.Nicotine-motivated behavior in Caenorhabditis elegans requires the nicotinic acetylcholine receptor subunits acr-5 and acr-15.Gustatory, trigeminal, and olfactory aspects of nicotine intake in three mouse strains.Cytochrome P450s And Alcoholic Liver Disease.
P2860
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P2860
Nicotine self-administration in mice is associated with rates of nicotine inactivation by CYP2A5.
description
2006 nî lūn-bûn
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2006年の論文
@ja
2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
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@zh-hant
name
Nicotine self-administration i ...... cotine inactivation by CYP2A5.
@en
Nicotine self-administration i ...... cotine inactivation by CYP2A5.
@nl
type
label
Nicotine self-administration i ...... cotine inactivation by CYP2A5.
@en
Nicotine self-administration i ...... cotine inactivation by CYP2A5.
@nl
prefLabel
Nicotine self-administration i ...... cotine inactivation by CYP2A5.
@en
Nicotine self-administration i ...... cotine inactivation by CYP2A5.
@nl
P2093
P1433
P1476
Nicotine self-administration i ...... cotine inactivation by CYP2A5.
@en
P2093
Dieter B Wildenauer
Eric C K Siu
Rachel F Tyndale
P2888
P304
P356
10.1007/S00213-006-0306-6
P577
2006-01-28T00:00:00Z