Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

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http://www.wikidata.org/entity/Q47142767
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase.Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.The LRRK2 signalling system.Back to the future: new target-validated Rab antibodies for evaluating LRRK2 signalling in cell biology and Parkinson's disease.Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration.Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria.Rab GTPases and Membrane Trafficking in Neurodegeneration.In Vitro Modeling of Leucine-Rich Repeat Kinase 2 (LRRK2) G2019S-Mediated Parkinson's Disease Pathology.Cellular and Molecular Basis of Neurodegeneration in Parkinson Disease.The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.Is Parkinson's disease a lysosomal disorder?A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brainLRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylationLRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis
P2860

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

Item
http://www.wikidata.org/entity/Q47142767
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh-hant
name
Systematic proteomic analysis ...... a connection to ciliogenesis.
@en
Systematic proteomic analysis ...... a connection to ciliogenesis.
@nl
type
label
Systematic proteomic analysis ...... a connection to ciliogenesis.
@en
Systematic proteomic analysis ...... a connection to ciliogenesis.
@nl
prefLabel
Systematic proteomic analysis ...... a connection to ciliogenesis.
@en
Systematic proteomic analysis ...... a connection to ciliogenesis.
@nl
P1433
P1476
P2093
P2860
P31
P356
P407
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Systematic proteomic analysis ...... s a connection to ciliogenesis
@en
P2093
P2860
P31
P356
P407
P478
P50
P577
P698
P921
P932