Inducible expression of (V600E) Braf using tyrosinase-driven Cre recombinase results in embryonic lethality.
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Report on the use of non-clinical studies in the regulatory evaluation of oncology drugsSomatic V600E BRAF Mutation in Linear and Sporadic Syringocystadenoma PapilliferumThyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice.Essential role for the SLK protein kinase in embryogenesis and placental tissue development.A murine model for the development of melanocytic nevi and their progression to melanoma.The melanomas: a synthesis of epidemiological, clinical, histopathological, genetic, and biological aspects, supporting distinct subtypes, causal pathways, and cells of origin.Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes.Applications of nanotechnology for melanoma treatment, diagnosis, and theranostics.Genetically engineered mouse models of melanoma.BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling.Rapid melanoma induction in mice expressing oncogenic BrafV600E using Mitf-cre.
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P2860
Inducible expression of (V600E) Braf using tyrosinase-driven Cre recombinase results in embryonic lethality.
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2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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name
Inducible expression of (V600E ...... esults in embryonic lethality.
@en
Inducible expression of
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type
label
Inducible expression of (V600E ...... esults in embryonic lethality.
@en
Inducible expression of
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prefLabel
Inducible expression of (V600E ...... esults in embryonic lethality.
@en
Inducible expression of
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P2093
P2860
P50
P1476
Inducible expression of (V600E ...... results in embryonic lethality
@en
P2093
Afshan McCarthy
Douglas Hedley
Lesley Ogilvie
Lionel Larue
Robert Hayward
Silvy Da Rocha Dias
P2860
P304
P356
10.1111/J.1755-148X.2009.00662.X
P577
2009-12-11T00:00:00Z