about
Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNAApoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunityLack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.CTLA-4 down-regulates the protective anticryptococcal cell-mediated immune responseDisrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblastsLupus Nephritis: Animal Modeling of a Complex Disease Syndrome Pathology.IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity.Amino acid catabolism: a pivotal regulator of innate and adaptive immunity.Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy.Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase.B Cell-Intrinsic IDO1 Regulates Humoral Immunity to T Cell-Independent Antigens.The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity.Molecular aspects of regulation of collagen gene expression in fibrosis.An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis.Selective Memory to Apoptotic Cell-Derived Self-Antigens with Implications for Systemic Lupus Erythematosus DevelopmentAn anatomical view on macrophages in tolerance.GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology.STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy?Type I Interferon in Chronic Virus Infection and Cancer.Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responsesThe PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment.Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism.A protective role of Mer receptor tyrosine kinase in nephrotoxic serum-induced nephritis.IDO-GCN2 and autophagy in inflammation.Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts.Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts.The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells.Polymorphisms of the TGF-beta1 promoter in tight skin (TSK) mice.Chemo-Immunotherapy: Role of Indoleamine 2,3-Dioxygenase in Defining Immunogenic Versus Tolerogenic Cell Death in the Tumor Microenvironment.Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen.CD8 T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained ImmunityThe Aryl Hydrocarbon Receptor: Connecting Immunity to the MicroenvironmentAn interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE)Cellular and molecular studies of B cells exhibiting reverse somatic mutation throughout lifeFcgammaRIIB deficiency leads to autoimmunity and a defective response to apoptosis in Mrl-MpJ miceRestoration of tolerance in lupus by targeted inhibitory receptor expressionHeterologous protein incites abnormal plasma cell accumulation and autoimmunity in MRL-MpJ miceApoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humansPeroxisome Proliferator-Activated Receptor-δ Acts within Peripheral Myeloid Cells to Limit Th Cell Priming during Experimental Autoimmune Encephalomyelitis
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Tracy L McGaha
@nl
Tracy L McGaha
@sl
Tracy L. McGaha
@en
Tracy L. McGaha
@es
type
label
Tracy L McGaha
@nl
Tracy L McGaha
@sl
Tracy L. McGaha
@en
Tracy L. McGaha
@es
prefLabel
Tracy L McGaha
@nl
Tracy L McGaha
@sl
Tracy L. McGaha
@en
Tracy L. McGaha
@es
P106
P1153
6602421272
P31
P496
0000-0003-4721-9301