about
Priming of protective T cell responses against virus-induced tumors in mice with human immune system componentsInflammasome-mediated dysbiosis regulates progression of NAFLD and obesityNLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cellsMicrobiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancerInflammasomes in health and diseaseMatrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes.Tonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma.Development and function of human innate immune cells in a humanized mouse modelMyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.Elevated Epstein-Barr virus-encoded nuclear antigen-1 immune responses predict conversion to multiple sclerosisHuman hemato-lymphoid system mice: current use and future potential for medicine.IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM.Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4.Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome.Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutationsDendritic cell-mediated activation-induced cytidine deaminase (AID)-dependent induction of genomic instability in human myeloma.Analysis of factors contributing to variation in the C57BL/6J fecal microbiota across German animal facilities.Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses.NK cells interactions with dendritic cells shape innate and adaptive immunity.Microenvironment-dependent growth of preneoplastic and malignant plasma cells in humanized mice.A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody productionRegulation of the antimicrobial response by NLR proteins.Improving human hemato-lymphoid-system mice by cytokine knock-in gene replacement.Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation.Antibiotics and the Intestinal Microbiome : Individual Responses, Resilience of the Ecosystem, and the Susceptibility to Infections.A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum.Enhancement of IFNγ Production by Distinct Commensals Ameliorates Salmonella-Induced Disease.Cyclic dinucleotides modulate induced type I IFN responses in innate immune cells by degradation of STING.Flagellin phase-dependent swimming on epithelial cell surfaces contributes to productive Salmonella gut colonisation.The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells.Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss.Humanized mouse model supports development, function, and tissue residency of human natural killer cells.Loss of CNFY toxin-induced inflammation drives Yersinia pseudotuberculosis into persistency.Shaping of Intestinal Microbiota in Nlrp6- and Rag2-Deficient Mice Depends on Community Structure.A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease.CD56brightCD16- killer Ig-like receptor- NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation.
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հետազոտող
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Till Strowig
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Till Strowig
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Till Strowig
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Till Strowig
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Till Strowig
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Till Strowig
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P106
P31
P496
0000-0003-0185-1459