about
Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitroMastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond networkDirect and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.Diverse cyclic seed peptides in the Mexican zinnia (Zinnia haageana).Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.Plasmin substrate binding site cooperativity guides the design of potent peptide aldehyde inhibitors.Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment.The evolution of Momordica cyclic peptides.Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library.Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors.Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold.The temperature activated HtrA protease from pathogen Chlamydia trachomatis acts as both a chaperone and protease at 37 degrees C.Natural and engineered plasmin inhibitors: applications and design strategies.Cyclotides as a basis for drug design.Recent progress towards pharmaceutical applications of disulfide-rich cyclic peptides.Disulfide-rich macrocyclic peptides as templates in drug design.Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies.Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists.Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells.Substrate-Guided Design of Selective FXIIa Inhibitors Based on the Plant-Derived Momordica cochinchinensis Trypsin Inhibitor-II (MCoTI-II) Scaffold.Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro.Translational diffusion of cyclic peptides measured using pulsed-field gradient NMR.Conformational Flexibility Is a Determinant of Permeability for Cyclosporin.Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum.Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.Effects of Cyclization on Peptide Backbone Dynamics.Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1Exploring experimental and computational markers of cyclic peptides: Charting islands of permeabilityCalcium-Mediated Allostery of the EGF FoldEffects of linker sequence modifications on the structure, stability, and biological activity of a cyclic α-conotoxinHighly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in PlasmaPotent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II
P50
Q27688934-B4E15414-9020-4A8D-B0EA-A4FD6A901A18Q28740672-9FE5CE6C-1180-477E-A49C-C99FD12E307BQ30825171-5869182D-ED3D-4865-85FE-9E625C9C5BF0Q31111152-01302C64-8E1F-4939-B879-3FBB3D918B1BQ33473073-9A23BAE3-C347-40C3-9039-62F7CDA0E83EQ34005781-F30D1BF5-136A-467B-BC81-9F244B55D341Q34233325-977FB88D-3B2A-469D-8832-605CBEBA6ED3Q34602948-25DE3639-B985-463E-A99B-4E1BFCD85031Q35400491-C2D00867-AC5C-48C8-8854-65E083AF853CQ35783014-0E6EAA8D-C5B5-42D4-839E-AC94DC949936Q35928328-D0CE3107-D6C6-4360-A3CA-FBBF9CB6B573Q36237689-F70A9026-C3F5-404B-BA85-E443E57F56F5Q37859510-F95F9F88-8ACE-4E87-97C5-F6AECA3940F8Q37975189-1A002B34-10EB-409E-A6DD-AA2987F7B2C0Q37999102-F9017F2B-9078-455C-9383-5CC699EF7F15Q38130737-D8CAC22D-E99C-417E-8C90-71A1BE197F82Q38197792-35AF37BD-FAFC-41C8-8396-6FF90F6EAF0EQ38834923-45B95388-61E3-471B-995C-ED13FE29F07DQ38965849-5F19B9E8-0012-4A38-A3CF-EBA042150581Q39355938-324D1DB4-A9E7-414E-86F3-6BC7AE98F32EQ39585367-FD114A72-71C8-4E14-ACE6-8A8CF3198AC2Q42408374-7E91E817-D6CA-490A-A04B-B9A217312862Q46909798-6779CF1E-421F-4ED2-AC67-B28ABACAB889Q50200262-BE5187E0-076B-45C7-BD47-73C3F6503F49Q51436737-724FADFD-C97A-400A-8CC6-DB0A1EEA7C4AQ53233135-92071D1B-E220-4155-AAE6-9FF9A2685891Q53394124-6313E08E-09DA-4FE1-844C-801AC5C25449Q58022615-871E6E16-16EA-40A4-B0D7-ABA11022AAD5Q87310490-BF87653A-B29D-4513-AA51-6E06B04117A5Q88532094-199619AF-51EB-4991-BD74-1FE47E21A173Q89107654-80C90FFD-70A2-4CAE-932D-FDD291E24C73Q90301008-752B662B-ACEB-41DD-AA19-D274BFD92D74Q90910514-2672121B-62AB-4726-BA5C-7BB161FAAB24
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Joakim E Swedberg
@nl
Joakim E Swedberg
@sl
Joakim E. Swedberg
@en
Joakim E. Swedberg
@es
type
label
Joakim E Swedberg
@nl
Joakim E Swedberg
@sl
Joakim E. Swedberg
@en
Joakim E. Swedberg
@es
altLabel
Joaquim E. Swedberg
@en
prefLabel
Joakim E Swedberg
@nl
Joakim E Swedberg
@sl
Joakim E. Swedberg
@en
Joakim E. Swedberg
@es
P1053
K-1501-2014
P106
P1153
35068682000
P21
P31
P3829
P496
0000-0003-4243-8660