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LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylationIntravital imaging of Ca(2+) signals in lymphocytes of Ca(2+) biosensor transgenic mice: indication of autoimmune diseases before the pathological onset.Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell developmentHuman tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunityVisualization of Probiotic-Mediated Ca2+ Signaling in Intestinal Epithelial Cells In VivoDefective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells.Mouse and human neutrophils induce anaphylaxis.Antigen-Specific IgG ameliorates allergic airway inflammation via Fcγ receptor IIB on dendritic cells.Placental extravillous cytotrophoblasts persistently express class I major histocompatibility complex molecules after human cytomegalovirus infection.Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malariaContribution of mast cell-derived interleukin-1β to uric acid crystal-induced acute arthritis in mice.An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers.Critical role of P1-Runx1 in mouse basophil development.Basophils help establish protective immunity induced by irradiated larval vaccination for filariasisSelective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndromeGATA-1 regulates the generation and function of basophils.Newly discovered roles for basophils: a neglected minority gains new respect.Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.The transfer of maternal antigen-specific IgG regulates the development of allergic airway inflammation early in life in an FcRn-dependent manner.Nonredundant roles of basophils in immunity.Emerging roles of basophils in protective immunity against parasites.Basophils have emerged as a key player in immunity.Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells.Basophil-derived IL-4 plays versatile roles in immunity.MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice.Emerging roles of basophils in allergic inflammation.Recent advances in understanding basophil-mediated Th2 immune responses.Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome.BASH-novel PKC-Raf-1 pathway of pre-BCR signaling induces kappa gene rearrangement.Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4+ T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis.Deficiency of BLNK hampers PLC-gamma2 phosphorylation and Ca2+ influx induced by the pre-B-cell receptor in human pre-B cells.Basophils contribute to pristane-induced Lupus-like nephritis model.Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R.The skin is an important bulwark of acquired immunity against intestinal helminths.Trogocytosis of peptide-MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils.Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks.Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling.Role of mast cells and basophils in IgE responses and in allergic airway hyperresponsiveness.Peanuts can contribute to anaphylactic shock by activating complement.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Hajime Karasuyama
@ast
Hajime Karasuyama
@en
Hajime Karasuyama
@es
Hajime Karasuyama
@nl
Hajime Karasuyama
@sl
type
label
Hajime Karasuyama
@ast
Hajime Karasuyama
@en
Hajime Karasuyama
@es
Hajime Karasuyama
@nl
Hajime Karasuyama
@sl
prefLabel
Hajime Karasuyama
@ast
Hajime Karasuyama
@en
Hajime Karasuyama
@es
Hajime Karasuyama
@nl
Hajime Karasuyama
@sl
P1053
A-7966-2011
P106
P21
P31
P3829
P496
0000-0003-0689-0836