about
TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminalsMultidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogsTargeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosisCharacterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cellsCharacterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5MPP5 recruits MPP4 to the CRB1 complex in photoreceptorsPals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cellsCrumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposureProtein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulationThe apical complex couples cell fate and cell survival to cerebral cortical development.c/CEPB, a chicken transcription factor of the leucine-zipper C/EBP family [corrected]In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy.A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomographyBone spicule pigment formation in retinitis pigmentosa: insights from a mouse model.GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectorsA family of drug transporters: the multidrug resistance-associated proteins.PALS1 is essential for retinal pigment epithelium structure and neural retina stratification.Estrogen-inducible and liver-specific expression of the chicken Very Low Density Apolipoprotein II gene locus in transgenic mice.Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.Pseudoxanthoma elasticum: a clinical, histopathological, and molecular update.A new CRB1 rat mutation links Müller glial cells to retinal telangiectasia.The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.Crumbs homologue 1 in polarity and blindness.Towards understanding CRUMBS function in retinal dystrophies.The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy.The CRB1 and adherens junction complex proteins in retinal development and maintenance.Pax-3-DNA interaction: flexibility in the DNA binding and induction of DNA conformational changes by paired domains.Genotypic and Phenotypic Characteristics of CRB1-Associated Retinal Dystrophies: A Long-Term Follow-up Study.Genetic and Molecular Approaches to Study Neuronal Migration in the Developing Cerebral CortexContribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides.Cloning and characterisation of a nuclear, site specific ssDNA binding protein.The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.MRP6 (ABCC6) detection in normal human tissues and tumors.Pax: gene regulators in the developing nervous system.Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1.Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models.Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.Specific tools for targeting and expression in Müller glial cells.
P50
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P50
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researcher
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հետազոտող
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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Jan Wijnholds
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P106
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7004225210
P31
P496
0000-0003-0099-460X