about
Recurring mutations found by sequencing an acute myeloid leukemia genomeDNA sequencing of a cytogenetically normal acute myeloid leukaemia genomeA high-resolution map of segmental DNA copy number variation in the mouse genomeSciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolutionDNMT3A Mutations in Acute Myeloid LeukemiaRecurrent DNMT3A mutations in patients with myelodysplastic syndromesUse of whole-genome sequencing to diagnose a cryptic fusion oncogene.Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental resultsImputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project.wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray dataSca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population.Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.Integrated analysis of germline and somatic variants in ovarian cancer.A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes.Integrated genomics of susceptibility to alkylator-induced leukemia in miceClonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing.Structural variation of the mouse natural killer gene complex.Roles of Sca-1 in hematopoietic stem/progenitor cell function.Murine models of human acute myeloid leukemia.Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in miceSequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progressionQuality of life and mood of patients and family caregivers during hospitalization for hematopoietic stem cell transplantation.Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML.U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicingRole of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.Health care utilization and end-of-life care for older patients with acute myeloid leukemiaMutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo.Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes.Clonal architecture of secondary acute myeloid leukemia.Prognostic understanding, quality of life and mood in patients undergoing hematopoietic stem cell transplantation.Therapy related acute myeloid leukemia in breast cancer survivors, a population-based study.Pharmacogenetics of alkylator-associated acute myeloid leukemia.Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML.Quantitative trait loci associated with susceptibility to therapy-related acute murine promyelocytic leukemia in hCG-PML/RARA transgenic miceClonal diversity of recurrently mutated genes in myelodysplastic syndromes.Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibilityThe impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells.Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantationStem cell expression of the AML1/ETO fusion protein induces a myeloproliferative disorder in mice.
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description
onderzoeker
@nl
researcher
@en
հետազոտող
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name
Timothy A. Graubert
@ast
Timothy A. Graubert
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Timothy A. Graubert
@es
Timothy A. Graubert
@nl
Timothy A. Graubert
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type
label
Timothy A. Graubert
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Timothy A. Graubert
@en
Timothy A. Graubert
@es
Timothy A. Graubert
@nl
Timothy A. Graubert
@sl
prefLabel
Timothy A. Graubert
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Timothy A. Graubert
@en
Timothy A. Graubert
@es
Timothy A. Graubert
@nl
Timothy A. Graubert
@sl
P106
P1153
6602867515
P21
P31
P496
0000-0002-7710-1171