Anticonvulsant activity of a nonpeptide galanin receptor agonist.MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics.A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleusSynthesis of galmic: a nonpeptide galanin receptor agonistDelineation of the peptide binding site of the human galanin receptorGalmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim testsFeverPhenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral testsPositive allosteric modulators to peptide GPCRs: a promising class of drugsReversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese miceA blood based 12-miRNA signature of Alzheimer disease patientsImpaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients.A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical testsGalanin and its receptors in neurological disordersThe brain galanin receptors: targets for novel antidepressant drugsIL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizuresG protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese miceCcl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue.Insulin causes hyperthermia by direct inhibition of warm-sensitive neurons.Metabolic characterization of a mouse deficient in all known leptin receptor isoforms.Hypothalamic and dietary control of temperature-mediated longevitySingle cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response Signaling asymmetry and an extension of chemical neuroanatomy.Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors.Interleukin-1beta contributes to the generation of experimental febrile seizuresThe promise of single-cell sequencing.GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models.Long distance signalling in volume transmission. Focus on clearance mechanisms.PNA oligomers as tools for specific modulation of gene expression.Regulation of feeding by galnon.Galanin inhibits acetylcholine release in the ventral hippocampus of the rat: histochemical, autoradiographic, in vivo, and in vitro studiesHigh-throughput FRET assay yields allosteric SERCA activatorsGalnon--a low-molecular weight ligand of the galanin receptors.Effect of galnon on induction of long-term potentiation in dentate gyrus of C57BL/6 mice.Ceramide mediates the rapid phase of febrile response to IL-1beta.Transgenic mice with a reduced core body temperature have an increased life span.Galanin overexpressing transgenic mice.Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test.A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses.Galanin in sensory neurons in the spinal cord.The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal.
P50
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P50
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(1948–) magyar származású svéd-amerikai agykutató
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Hongaars neurowetenschapper
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neurocientífico húngaro
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neurocientíficu suecu
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عالم أعصاب مجري
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