An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases
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Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variantsLoci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel diseaseContribution of Genetic Factors to Sjögren's Syndrome and Sjögren's Syndrome Related LymphomagenesisInterferons in Sjögren's Syndrome: Genes, Mechanisms, and EffectsInsights into interferon regulatory factor activation from the crystal structure of dimeric IRF5Recent advances in the genetics of autoimmune diseaseGenetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritisA functional 12T-insertion polymorphism in the ATP1A1 promoter confers decreased susceptibility to hypertension in a male Sardinian populationAn IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin MiceMeta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47Genetic risk factors in lupus nephritis and IgA nephropathy--no support of an overlap.IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).Proteins That Underlie Neoplastic Progression of Ulcerative Colitis.Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome.Genetic associations in type I interferon related pathways with autoimmunityGenetic association study of TNFAIP3, IFIH1, IRF5 polymorphisms with polymyositis/dermatomyositis in Chinese Han population.Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.Progress and promise of genome-wide association studies for human complex trait geneticsGenotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms.The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably shareProinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages.Two functional variants of IRF5 influence the development of macular edema in patients with non-anterior uveitisAssociation of IRF5 polymorphisms with activation of the interferon alpha pathwayAspects of innate immunity in Sjögren's syndrome.Variants of Interferon Regulatory Factor 5 are Associated with Neither Neuromyelitis Optica Nor Multiple Sclerosis in the Southeastern Han Chinese Population.Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses.Modulation of macrophage efferocytosis in inflammation.IRF5 gene polymorphisms in melanomaInterferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous SystemGenetics of SLE: functional relevance for monocytes/macrophages in diseasePsoriasis, psoriatic arthritis and increased risk of incident Crohn's disease in US women.Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk LociA risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populationsSpecific detection of interferon regulatory factor 5 (IRF5): A case of antibody inequality.A two-marker haplotype in the IRF5 gene is associated with inflammatory bowel disease in a North American cohort.IRF5 regulates lung macrophages M2 polarization during severe acute pancreatitis in vitro.IRF5 is a specific marker of inflammatory macrophages in vivo.In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.Regulation of T helper cell differentiation by interferon regulatory factor family members.
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P2860
An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases
description
article
@en
im Dezember 2007 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в грудні 2007
@uk
ലേഖനം
@ml
name
An insertion-deletion polymorp ...... of inflammatory bowel diseases
@en
An insertion-deletion polymorphism in the interferon regulatory Factor 5
@nl
type
label
An insertion-deletion polymorp ...... of inflammatory bowel diseases
@en
An insertion-deletion polymorphism in the interferon regulatory Factor 5
@nl
prefLabel
An insertion-deletion polymorp ...... of inflammatory bowel diseases
@en
An insertion-deletion polymorphism in the interferon regulatory Factor 5
@nl
P2093
P50
P356
P1476
An insertion-deletion polymorp ...... of inflammatory bowel diseases
@en
P2093
André Van Gossum
Ann-Christin Wiman
Cécile Libioulle
Denis Franchimont
Edouard Louis
Gudlaug Kristjansdottir
Jacques Belaiche
Vincent Bours
Vinciane Dideberg
P304
P356
10.1093/HMG/DDM259
P407
P577
2007-12-15T00:00:00Z