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Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressivenessGuidelines for the use and interpretation of assays for monitoring autophagySiva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathwayActive stromelysin-3 (MMP-11) increases MCF-7 survival in three-dimensional Matrigel culture via activation of p42/p44 MAP-kinaseProteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteasesCharacterization and purification of T lymphocyte aminopeptidase B: a putative marker of T cell activationAnti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa barkTumor cell-mediated induction of the stromal factor stromelysin-3 requires heterotypic cell contact-dependent activation of specific protein kinase C isoformsAcadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell deathInjection of Staphylococcus aureus EDIN by the Bacillus anthracis protective antigen machinery induces vascular permeability.Tumor suppressor function of miR-483-3p on squamous cell carcinomas due to its pro-apoptotic properties.Study of a growth hormone-regulated protein secreted by rat hepatocytes: cDNA cloning, anti-protease activity and regulation of its synthesis by various hormones.Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.Severe thymic atrophy in a mouse model of skin inflammation accounts for impaired TNFR1 signaling.Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.Successful re-treatment of a relapsed V600E mutated HCL patient with low-dose vemurafenib.Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia.Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.Involvement of mast cells in gastritis caused by Helicobacter pylori: a potential role in epithelial cell apoptosis.The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMMLThe anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia.Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced deathResistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic fluxBCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic miceDifferentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell deathInhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.Total genomic alteration as measured by SNP-array-based molecular karyotyping is predictive of overall survival in a cohort of MDS or AML patients treated with azacitidine.How recent advances in high-risk myelodysplastic syndrome physiopathology may impact future treatments.Thrombin and thrombin receptor agonist peptide induce early events of T cell activation and synergize with TCR cross-linking for CD69 expression and interleukin 2 production.Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.Synthesis and anti-cancer activities of new sulfonamides 4-substituted-triazolyl nucleosides.In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies.Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines.Autophagy, a key mechanism of oncogenesis and resistance in leukemia.Ultrasound-assisted one-pot synthesis of anti-CML nucleosides featuring 1,2,3-triazole nucleobase under iron-copper catalysis.Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Patrick Auberger
@ast
Patrick Auberger
@en
Patrick Auberger
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Patrick Auberger
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type
label
Patrick Auberger
@ast
Patrick Auberger
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Patrick Auberger
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Patrick Auberger
@nl
altLabel
Patrick AUBERGER
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prefLabel
Patrick Auberger
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Patrick Auberger
@en
Patrick Auberger
@es
Patrick Auberger
@nl
P214
P1053
G-1491-2013
P106
P214
P31
P496
0000-0002-2481-8275
P735
P7859
viaf-172229620