about
sameAs
P688
IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomesSASH1 is a scaffold molecule in endothelial TLR4 signalingIKKβ phosphorylation regulates RPS3 nuclear translocation and NF-κB function during infection with Escherichia coli strain O157:H7Binding of manumycin A inhibits IkappaB kinase beta activityFoxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cellsThe zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-κB signalingNLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathwaysThe IkappaB kinase complex: master regulator of NF-kappaB signalingIKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activationIkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIKThe E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMOTumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phasesIkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3aMixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergisticallyChaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMACrystal structure of inhibitor of κB kinase βIκB kinase phosphorylation of SNAP-23 controls platelet secretionPhosphorylation of SNAP-23 by IkappaB kinase 2 regulates mast cell degranulationPhosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activationINCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generationA structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylationTfR1 interacts with the IKK complex and is involved in IKK-NF-κB signallingGain-of-function mutation causes human combined immune deficiency
P921
Q50257063-26258123-E487-42E4-96E3-596EEC958006Q50259852-DB578BEB-122D-493C-AE3D-5D91E3629629Q50260050-1B5F444E-6C38-4B8C-824F-7548E741D0A3Q50271265-B0A0656B-E873-4765-B607-D2B02A202EBAQ50271271-E16315EC-47C8-4396-BE1F-9058B4F8443FQ50289677-A9CC6F1B-5363-43AA-86EC-07E963FE2073Q50291696-C5392594-6D9C-452D-9CCB-5063F73F6876
P527
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Inhibitor of nuclear factor kappa B kinase subunit beta
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
IKK2
@pl
Inhibitor of nuclear factor kappa B kinase subunit beta
@en
Inhibitor of nuclear factor kappa B kinase subunit beta
@nl
type
label
IKK2
@pl
Inhibitor of nuclear factor kappa B kinase subunit beta
@en
Inhibitor of nuclear factor kappa B kinase subunit beta
@nl
altLabel
I-kappa-B kinase 2
@en
I-kappa-B-kinase beta
@en
IKBKB
@en
IKK-B
@en
IKK2
@en
NFKBIKB
@en
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
@en
inhibitor of nuclear factor kappa-B kinase subunit beta
@en
nuclear factor NF-kappa-B inhibitor kinase beta
@en
prefLabel
IKK2
@pl
Inhibitor of nuclear factor kappa B kinase subunit beta
@en
Inhibitor of nuclear factor kappa B kinase subunit beta
@nl
P527
P637
P638
P680
P681
P682
P705
P352
P637
P2888
P31
P352
P527
P637
NP_001177649
NP_001229707
XP_005273547
XP_005273548
XP_005273549
XP_005273550
XP_005273551
XP_005273552
XP_005273553
P638
P680
P681
P682
P702
P703
P705
ENSP00000339151
ENSP00000404920
ENSP00000427978
ENSP00000428186
ENSP00000428799
ENSP00000428892
ENSP00000428922
ENSP00000429239
ENSP00000429319
ENSP00000429357