about
Managing risks in drug discovery: reproducibility of published findingsDirect stimulation of receptor-controlled phospholipase D1 by phospho-cofilinInhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesisRGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recyclingAlterations in reversible protein histidine phosphorylation as intracellular signals in cardiovascular diseaseActivation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbetap63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same geneHyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived CardiomyocytesActivation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Specific activation of Gsalpha by an NDPK B.Gbetagamma complex in H10 cellsOxytocin receptors differentially signal via Gq and Gi proteins in pregnant and nonpregnant rat uterine myocytes: implications for myometrial contractility.The interaction of nucleoside diphosphate kinase B with Gbetagamma dimers controls heterotrimeric G protein function.Alterations in cardiac DNA methylation in human dilated cardiomyopathyGalpha q allosterically activates and relieves autoinhibition of p63RhoGEF.Dual role of protein kinase C on BK channel regulation.RGS5 promotes arterial growth during arteriogenesisExpression of ten RGS proteins in human myocardium: functional characterization of an upregulation of RGS4 in heart failure.Nucleoside diphosphate kinase as protein histidine kinase.The BTB-Kelch protein KLEIP controls endothelial migration and sprouting angiogenesis.Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis.Regulators of G-protein signalling: multifunctional proteins with impact on signalling in the cardiovascular system.M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity.RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response.Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegansCan a GDP-liganded G-protein be active?Identification of intracellular proteins and signaling pathways in human endothelial cells regulated by angiotensin-(1-7)High energy phosphate transfer by NDPK B/Gbetagammacomplexes--an alternative signaling pathway involved in the regulation of basal cAMP production.Anaphylactic shock depends on endothelial Gq/G11.The natriuretic peptide/guanylyl cyclase--a system functions as a stress-responsive regulator of angiogenesis in miceFurther intracellular proteins and signaling pathways regulated by angiotensin-(1-7) in human endothelial cells.Dynamics of Gαq-protein-p63RhoGEF interaction and its regulation by RGS2.Alignment-Annotator web server: rendering and annotating sequence alignments.G protein-coupled receptor kinase 2 promotes cardiac hypertrophyNucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.Calcium/Calmodulin-Dependent Protein Kinase II Activity Persists During Chronic β-Adrenoceptor Blockade in Experimental and Human Heart Failure.RhoGEF17, a Rho-specific guanine nucleotide exchange factor activated by phosphorylation via cyclic GMP-dependent kinase Iα.Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin αvβ5-induced secretion of VEGF-A.Nucleoside diphosphate kinase B regulates angiogenic responses in the endothelium via caveolae formation and c-Src-mediated caveolin-1 phosphorylation.Nucleoside diphosphate kinase B is required for the formation of heterotrimeric G protein containing caveolae.Through scaffolding and catalytic actions nucleoside diphosphate kinase B differentially regulates basal and β-adrenoceptor-stimulated cAMP synthesis.Reduced expression of Rho guanine nucleotide dissociation inhibitor-alpha modulates the cytotoxic effect of busulfan in HEK293 cells.
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Thomas Wieland
@ast
Thomas Wieland
@en
Thomas Wieland
@es
Thomas Wieland
@nl
type
label
Thomas Wieland
@ast
Thomas Wieland
@en
Thomas Wieland
@es
Thomas Wieland
@nl
prefLabel
Thomas Wieland
@ast
Thomas Wieland
@en
Thomas Wieland
@es
Thomas Wieland
@nl
P108
P214
P244
P106
P108
P214
P244
no2006007298
P31
P496
0000-0001-8262-8261
P734
P735
P7859
lccn-no2006007298