about
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activationA TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback controlCARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cellsStructural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspaseSyk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunityBimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB inductionCard9 controls a non-TLR signalling pathway for innate anti-fungal immunityThe Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulationA respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signalingAn innate antiviral pathway acting before interferons at epithelial surfaces.Oncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas.The adaptor molecule CARD9 is essential for tuberculosis control.Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency.Cks1 is required for tumor cell proliferation but not sufficient to induce hematopoietic malignanciesBcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications.Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skinTGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function.Prdm6 is essential for cardiovascular development in vivoGP130 activation induces myeloma and collaborates with MYC.Pathogenic fungi regulate immunity by inducing neutrophilic myeloid-derived suppressor cells.Bcl10 and Malt1 control lysophosphatidic acid-induced NF-kappaB activation and cytokine production.Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.Inflammatory signal transduction from the Fc epsilon RI to NF-kappa B.The SYK tyrosine kinase: a crucial player in diverse biological functions.Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis.A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency.Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus ArteriosusThe Nlrp3 inflammasome regulates acute graft-versus-host disease.Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.CARD9 signaling in the innate immune response.B-cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production.Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death.Experimental cerebral malaria develops independently of caspase recruitment domain-containing protein 9 signalingThe NF-κB signaling protein Bcl10 regulates actin dynamics by controlling AP1 and OCRL-bearing vesicles.Bcl10 links saturated fat overnutrition with hepatocellular NF-kB activation and insulin resistance.
P50
Q24298225-966B16D8-4688-402A-855F-1B63D1C567D1Q24621472-EA63A530-BC30-4FDB-933B-060FF4E4D5D0Q24675332-89F7B487-A36D-477D-987A-6C9F96B4F3E1Q27685382-B4D4EE1E-0693-43D0-9344-3CEC2C35E9A5Q28118774-79B629B2-97CD-4189-ABCD-DD556C8D4A17Q28198772-2D278ED5-504F-41E1-A78B-500C1FE1F5BAQ28504584-28E2B312-B8A4-4466-97B0-0A180193EF44Q28587567-B8821F52-41C7-43F5-9834-2EFDBDCC6E4AQ28608443-C88A2E00-C862-4CB6-B522-6696C1CD1153Q30278039-18CBC8F8-19D5-48E7-BE22-B8DF949BCE74Q30375911-0116435A-1704-4401-8522-39F85468C023Q33794955-E9BD64EC-5B9A-41A2-A3D7-AC32AE51089AQ34099417-FA5533CA-E3EE-4D81-A34C-796F5424B75FQ34107503-86EC4116-26F3-4420-916E-5BBE0E9C7231Q34206229-A2259B82-2C1C-44DB-993C-BF043469B959Q34279980-1927DEDF-FDE7-4766-9245-D267CA7B0E71Q34315544-6DDA0D46-D135-4CDC-A3CE-6C8B7830CF6CQ34583474-C5F1B8AE-C6AC-436D-839F-786304767290Q34920323-C40FEA65-2CEA-4E38-ADD6-E7EA20244CF6Q34995688-7C6090DF-25EF-4D67-9C7B-C76BA23F2A6AQ35014257-4407E979-062F-4E51-B86E-0D58074D8D92Q35054101-E0E03F28-A75E-4507-A8D7-B9F567A45352Q35145350-D3298E5B-233D-41DF-B41C-B5B10B8163CDQ35450411-2397740D-8D39-4E77-8D0F-A4FD9103BD9BQ35575886-663EA7A0-649C-418F-A12F-F08B56122B58Q35906438-808653FD-E5F3-4040-A98C-5EFDA903E0B4Q36657292-1533307A-8AFD-47D8-8CB7-C1B85F9C6256Q36662082-61BACD35-AEB6-4DBF-8D82-D5400C0E284AQ36699754-39BFE797-04A5-40BF-B10C-6A0AC649F6CDQ36979888-DB3A9D4C-1D7B-4B9C-95D2-5CB09959BFD6Q37005118-C17A15C1-9D83-4152-94D0-5F673395315CQ37194967-3FDED6A9-9873-482A-AE1F-853F727A6535Q37331568-F5527572-909A-401E-8A7B-C32E4E04069BQ37348430-98D743F5-C91F-4C7B-B2A8-3CAEF391F124Q38983753-AAF7A658-D4B3-472A-8699-7A2D382AE7BCQ39000597-728E5F6D-5F4E-47FE-B74F-170C55C460CBQ39015420-4CF18444-D796-4D01-9F60-55EA16CE15C2Q39040766-E57E7DF0-AECA-4A63-AF16-6206209C5722Q39244424-A87DC22A-2012-47C0-8B2B-1D0409AC17FAQ39329540-86EB805B-5597-473B-8406-10364528863D
P50
description
farmacoloog
@nl
researcher ORCID ID = 0000-0002-8381-3597
@en
name
Jürgen Maximilian Ruland
@de
Jürgen Ruland
@en
Jürgen Ruland
@es
Jürgen Ruland
@nl
type
label
Jürgen Maximilian Ruland
@de
Jürgen Ruland
@en
Jürgen Ruland
@es
Jürgen Ruland
@nl
prefLabel
Jürgen Maximilian Ruland
@de
Jürgen Ruland
@en
Jürgen Ruland
@es
Jürgen Ruland
@nl
P214
P227
P1053
Q-6680-2018
P21
P214
P227
P31
P496
0000-0002-8381-3597
P735
P7859
viaf-196557703