about
Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channelsDirect interaction of the calcium sensor protein synaptotagmin I with a cytoplasmic domain of the alpha1A subunit of the P/Q-type calcium channelGroup X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in miceChlorotoxin: a helpful natural scorpion peptide to diagnose glioma and fight tumor invasionGene regulation by voltage-dependent calcium channelsPharmacological profiling of Orthochirus scrobiculosus toxin 1 analogs with a trimmed N-terminal domainCacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsyTriadin (Trisk 95) overexpression blocks excitation-contraction coupling in rat skeletal myotubesCD38-dependent ADP-ribosyl cyclase activity in developing and adult mouse brainCombining Ca2+ and membrane potential imaging in single neuronsCombining calcium imaging with other optical techniquesEvolution of maurotoxin conformation and blocking efficacy towards Shaker B channels during the course of folding and oxidation in vitroDisulfide bridge reorganization induced by proline mutations in maurotoxin.Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity.SRP-27 is a novel component of the supramolecular signalling complex involved in skeletal muscle excitation-contraction coupling.Maurocalcine as a non toxic drug carrier overcomes doxorubicin resistance in the cancer cell line MDA-MB 231Scorpion alpha-like toxins, toxic to both mammals and insects, differentially interact with receptor site 3 on voltage-gated sodium channels in mammals and insects.The I-II loop of the Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit.Effect of maurotoxin, a four disulfide-bridged toxin from the chactoid scorpion Scorpio maurus, on Shaker K+ channels.In vivo expression of G-protein beta1gamma2 dimer in adult mouse skeletal muscle alters L-type calcium current and excitation-contraction coupling.Diversity of folds in animal toxins acting on ion channels.Occurrence of the synthetic analgesic tramadol in an African medicinal plant.Contribution of the functional dyad of animal toxins acting on voltage-gated Kv1-type channels.Functional coupling of Rab3-interacting molecule 1 (RIM1) and L-type Ca2+ channels in insulin release.Rim1 modulates direct G-protein regulation of Ca(v)2.2 channels.Transient loss of voltage control of Ca2+ release in the presence of maurocalcine in skeletal muscle.Fractionation and proteomic analysis of the Walterinnesia aegyptia snake venom using OFFGEL and MALDI-TOF-MS techniques.A retro-biosynthetic approach to the prediction of biosynthetic pathways from position-specific isotope analysis as shown for tramadolAntipyretic and antinociceptive effects of Nauclea latifolia root decoction and possible mechanisms of action.Anticonvulsant effects of iridoid glycosides fraction purified from Feretia apodanthera Del. (Rubiaceae) in experimental mice models of generalized tonic-clonic seizures.FRET-Based Nanobiosensors for Imaging Intracellular Ca²⁺ and H⁺ Microdomains.How do G proteins directly control neuronal Ca2+ channel function?Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus, improves sperm motility and fertilization in different mammalian species.In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptideThe S218L familial hemiplegic migraine mutation promotes deinhibition of Ca(v)2.1 calcium channels during direct G-protein regulation.Combining Ca2+ imaging with -glutamate photorelease.Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotidesA Novel Platinum-Maurocalcine Conjugate Induces Apoptosis of Human Glioblastoma Cells by Acting through the ROS-ERK/AKT-p53 Pathway.PTEN-regulated AKT/FoxO3a/Bim signaling contributes to Human cell glioblastoma apoptosis by platinum-maurocalcin conjugate.Nauclea latifolia: biological activity and alkaloid phytochemistry of a West African tree.
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0002-2782-9615
@en
name
Michel De Waard
@ast
Michel De Waard
@en
Michel De Waard
@es
Michel De Waard
@nl
type
label
Michel De Waard
@ast
Michel De Waard
@en
Michel De Waard
@es
Michel De Waard
@nl
prefLabel
Michel De Waard
@ast
Michel De Waard
@en
Michel De Waard
@es
Michel De Waard
@nl
P106
P31
P496
0000-0002-2782-9615