about
Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signallingDifferential role for CD277 as a co-regulator of the immune signal in T and NK cellsFunctional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinaseThe SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule.Dok-4 is a novel negative regulator of T cell activation.Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locusConstitutive AKT activation in follicular lymphoma.Dok1 and Dok2 proteins regulate natural killer cell development and function.Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells.Hepatitis C virus fails to activate NF-κB signaling in plasmacytoid dendritic cellsDual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic CellsTravel informations on the Tec kinases during lymphocyte activation.An Emerging Role for PI5P in T Cell Biology.In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation.Regions of the CD8 molecule involved in the regulation of CD2-mediated activation.Modulation of T Cell Activation in Obesity.Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA.Analysis of signaling events by dynamic phosphoflow cytometry.Evidence for a positive role of PtdIns5P in T-cell signal transduction pathways.ADAPted secretion of cytokines in NK cells.Flow cytometric analysis of intracellular phosphoproteins in human monocytes.Evolutionary and expression analyses reveal a pattern of ancient duplications and functional specializations in the diversification of the Downstream of Kinase (DOK) genes.Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.CD28 deletion improves obesity-induced liver steatosis but increases adiposity in mice.Dok1 and Dok2 Proteins Regulate Cell Cycle in Hematopoietic Stem and Progenitor Cells.Triggering CD 28 molecules synergize with CD 2 (T 11.1 and T 11.2)-mediated T cell activation.A non-conserved amino acid variant regulates differential signalling between human and mouse CD28.T Cells on Engineered Substrates: The Impact of TCR Clustering Is Enhanced by LFA-1 EngagementMutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML)TCR and CD28 Concomitant Stimulation Elicits a Distinctive Calcium Response in Naive T CellsVitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer.Cholera toxin inhibits the increase in cytoplasmic free calcium induced via the CD2 pathway of human T-lymphocyte activationT cell activation via the CD2 molecule is associated with protein kinase C translocation from the cytosol to the plasma membraneRegulation of CD2-mediated human T cell activation: anti-CD8 monoclonal antibodies inhibit CD2-mediated rise in intracellular calciumPD-L2 is expressed on activated human T cells and regulates their functionFit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-4865-0400
@en
name
Jacques A Nunes
@ast
Jacques A Nunes
@en
Jacques A Nunes
@nl
type
label
Jacques A Nunes
@ast
Jacques A Nunes
@en
Jacques A Nunes
@nl
prefLabel
Jacques A Nunes
@ast
Jacques A Nunes
@en
Jacques A Nunes
@nl
P106
P21
P31
P496
0000-0003-4865-0400