IFI16 filament formation in salivary epithelial cells shapes the anti-IFI16 immune response in Sjögren's syndrome

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IFI16 filament formation in salivary epithelial cells shapes the anti-IFI16 immune response in Sjögren's syndrome

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wetenschappelijk artikel

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наукова стаття, опублікована у вересні 2018

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IFI16 filament formation in sa ...... response in Sjögren's syndrome

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IFI16 filament formation in sa ...... response in Sjögren's syndrome

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IFI16 filament formation in sa ...... response in Sjögren's syndrome

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IFI16 filament formation in sa ...... response in Sjögren's syndrome

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IFI16 filament formation in sa ...... response in Sjögren's syndrome

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IFI16 filament formation in sa ...... response in Sjögren's syndrome

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P1476

IFI16 filament formation in sa ...... response in Sjögren's syndrome

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Antony Rosen

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Brendan Antiochos

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Jungsan Sohn

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Livia Casciola-Rosen

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Mariusz Matyszewski

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Mitochondrial DNA stress primes the antiviral innate immune response

IFI16 is an innate immune sensor for intracellular DNA

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV

Identification of specific autoantigens in Sjögren's syndrome by SEREX

The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex.

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

The mammalian PYHIN gene family: phylogeny, evolution and expression

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scholarly article

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10.1172/JCI.INSIGHT.120179

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English

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P478

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2018-09-20T00:00:00Z

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30232276

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6237237

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