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PLEKHG2 promotes heterotrimeric G protein βγ-stimulated lymphocyte migration via Rac and Cdc42 activation and actin polymerization.Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeletonMicrocephaly-dystonia due to mutated PLEKHG2 with impaired actin polymerization.Ablation of the GNB3 gene in mice does not affect body weight, metabolism or blood pressure, but causes bradycardia.A critical role of Gbetagamma in tumorigenesis and metastasis of breast cancer.Characterization of a novel mouse model with genetic deletion of CD177The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis.Gβγ signaling controls the polarization of zebrafish primordial germ cells by regulating Rac activityInteraction of Gbetagamma with RACK1 and other WD40 repeat proteins.RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival.Upregulated WDR26 serves as a scaffold to coordinate PI3K/ AKT pathway-driven breast cancer cell growth, migration, and invasion.The Gβ3 splice variant associated with the C825T gene polymorphism is an unstable and functionally inactive proteinGβ1 controls collective cell migration by regulating the protrusive activity of leader cells in the posterior lateral line primordium.Gβ1 is required for neutrophil migration in zebrafish.Identification and expression patterns of members of the protease-activated receptor (PAR) gene family during zebrafish development.RACK1 regulates specific functions of Gbetagamma.Immunohistochemical localisation of alpha1B-adrenergic receptors in the rat iris.Inhibiting G protein βγ signaling blocks prostate cancer progression and enhances the efficacy of paclitaxel.Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA.S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy.Alpha1-adrenergic receptor signaling via Gh is subtype specific and independent of its transglutaminase activityDEP domains: More than just membrane anchorsElimination of SOX2/OCT4-Associated Prostate Cancer Stem Cells Blocks Tumor Development and Enhances Therapeutic Response
P50
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P50
description
researcher ORCID ID = 0000-0001-7316-7125
@en
wetenschapper
@nl
name
Songhai Chen
@ast
Songhai Chen
@en
Songhai Chen
@es
Songhai Chen
@nl
type
label
Songhai Chen
@ast
Songhai Chen
@en
Songhai Chen
@es
Songhai Chen
@nl
prefLabel
Songhai Chen
@ast
Songhai Chen
@en
Songhai Chen
@es
Songhai Chen
@nl
P1153
7410249366
P31
P496
0000-0001-7316-7125