about
Fluorescence ratio imaging microscopy: temporal and spatial measurements of cytoplasmic pHFluorescent protein biosensors applied to microphysiological systemsIdentifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discoveryKeratocytes generate traction forces in two phases.In vitro platforms for evaluating liver toxicity.Fluorescence photobleaching recovery in solutions of labeled actin.Analysis of rhodamine and fluorescein-labeled F-actin diffusion in vitro by fluorescence photobleaching recovery.A fluorescent protein biosensor of myosin II regulatory light chain phosphorylation reports a gradient of phosphorylated myosin II in migrating cells.Contractile basis of ameboid movement. VII. Aequorin luminescence during ameboid movement, endocytosis, and capping.Contractile basis of ameboid movement. VII. The distribution of fluorescently labeled actin in living amebas.Distribution of actin in spreading macrophages: a comparative study on living and fixed cells.Acidification of phagosomes is initiated before lysosomal enzyme activity is detectedMicrospectrofluorometry by digital image processing: measurement of cytoplasmic pH.A method for incorporating macromolecules into adherent cells.Fc-receptor-mediated phagocytosis occurs in macrophages without an increase in average [Ca++]i.Relative distribution of actin, myosin I, and myosin II during the wound healing response of fibroblasts.In vitro models of tail contraction and cytoplasmic streaming in amoeboid cells.Mobility of cytoplasmic and membrane-associated actin in living cells.A human liver microphysiology platform for investigating physiology, drug safety, and disease modelsPreparation and characterization of a new molecular cytochemical probe: 5-iodoacetamidofluorescein-labeled actin.Potential of machine-vision light microscopy in toxicologic pathology.Myosin II transport, organization, and phosphorylation: evidence for cortical flow/solation-contraction coupling during cytokinesis and cell locomotion.Automated light microscopy for the study of the brain: cellular and molecular dynamics, development, and tumorigenesis.A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine.Applications of cellular systems biology in breast cancer patient stratification and diagnostics.Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways.Spatial Statistics for Segmenting Histological Structures in H&E Stained Tissue Images.Liver metastases: Microenvironments and ex-vivo models.Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy.Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers.Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.Fluorescently labelled molecules as probes of the structure and function of living cells.A photocross-linking fluorescent indicator of mitochondrial membrane potential.Heterogeneity of the changes in cytoplasmic pH upon serum stimulation of quiescent fibroblasts.Antigen presentation and cytotoxic T lymphocyte killing studied in individual, living cells.Liver 'organ on a chip'.Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology.Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images.Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes.
P50
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P50
description
Forscher
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chercheur
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investigador
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researcher
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ricercatore
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wetenschapper
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研究者
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name
D L Taylor
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D L Taylor
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D L Taylor
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D L Taylor
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type
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D L Taylor
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D L Taylor
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D L Taylor
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D L Taylor
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D L Taylor
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D L Taylor
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D L Taylor
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D L Taylor
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P31
P496
0000-0001-6947-1343