about
P688
Resistance to apoptosis in human cells conferred by telomerase function and telomere stabilityIn vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAsHypoxia extends the life span of vascular smooth muscle cells through telomerase activation.Human telomerase contains two cooperating telomerase RNA molecules.The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitorEndothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunctionThe AAA-ATPase NVL2 is a telomerase component essential for holoenzyme assemblyDifferential regulation of telomerase activity by six telomerase subunitsSpecificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivoPML-IV functions as a negative regulator of telomerase by interacting with TERTTelomerase modulates Wnt signalling by association with target gene chromatinHuman POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.Modulation of human telomerase reverse transcriptase in hepatocellular carcinomaTelomerase reverse transcriptase regulates microRNAsReconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRTAn enhanced H/ACA RNP assembly mechanism for human telomerase RNAPinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual rolesHuman UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replicationExtension of life-span by introduction of telomerase into normal human cellsAn RNA-dependent RNA polymerase formed by TERT and the RMRP RNAHuman protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitroHuman telomerase acts as a hTR-independent reverse transcriptase in mitochondriaIncreased Stability of Nucleolar PinX1 in the Presence of TERTThe human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeatsStructure of active dimeric human telomerase.HTLV-1 bZIP factor impedes the menin tumor suppressor and upregulates JunD-mediated transcription of the hTERT geneSingle-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangsCurcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERTFunctional requirement of p23 and Hsp90 in telomerase complexesReconstitution of human telomerase activity in vitroProtein RNA and protein protein interactions mediate association of human EST1A/SMG6 with telomeraseRegulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domainCryo-EM structure of substrate-bound human telomerase holoenzyme.
P921
Q22003740-B57C1EE1-86FB-4831-BE64-9C2D6422A6A1Q22253860-47C10D5E-12D5-4791-A7BE-E214858C5E0CQ24291155-468E31A3-92E7-4730-B8DD-64A77887ECECQ24291388-C35C68D3-5E64-42AC-9C44-29C7486BA060Q24291889-357420BD-46C5-4B08-8924-D248208797B9Q24292963-2E98DEF5-05C6-4DC6-83E1-669D69729BCAQ24301283-02DB6EB3-6399-4AC4-9C93-8C3944EAFFFFQ24301904-5165CFCC-CB33-4DA1-8E73-D070EACB41A5Q24305098-09AD40F3-132B-4D2C-A998-C7FFC062BCF7Q24309336-78ECAB30-D771-4CA3-8407-3C6B0845484AQ24310084-83D06EBB-F9B3-48B0-A6AA-F276CDAED000Q24310177-C5269632-6970-4EFC-B09C-2D7DD5871569Q24313131-90ED14BA-7D7D-4D07-97D2-F3C61EAA40FEQ24313154-0C974ED6-26A7-4E68-91CD-FF631A5535AAQ24313396-07EEBB69-E247-419D-87BE-786A46C76693Q24316597-20FCD2CA-BF6A-4B73-85AD-3063664DA649Q24319715-0C62A0C3-46FE-4545-87ED-050FBFC3B288Q24320933-BA5875BC-9B2C-4B5E-9C98-81D667B5CFFDQ24336088-104157A1-6116-4316-8D2A-A0798D6DCB8DQ24336971-E9CE78BE-3D3A-45A4-B145-CA14AF928713Q24337394-25A1E350-10EB-495A-8317-675AFAD6C8E6Q24338425-CE738D1D-C3D0-4C20-9F05-216388DB91B3Q24338508-78B30DA4-4835-4094-B97C-D3273F023E47Q24339608-B65789ED-6569-4169-844F-3542B9B74D50Q28115347-018F662B-6BD3-4484-8357-00A2777F8C9AQ28115378-7CB16E36-0F85-4E30-90E7-4B67AC6D4DAEQ28115535-6F7A5432-1A51-4FC2-9CB5-C558EE9A22B4Q28115618-96E6E4B1-255B-4CE3-90AD-9BB4737A2E45Q28115669-2EC557DE-4C32-4073-BCF4-02E3F1E5B8EEQ28116966-A66F8BDF-9A0F-494E-BA21-91C8F07290F2Q28117179-F14FB938-D191-4FCA-9782-8B5FA453250EQ28119138-4C07E337-C317-44C0-A393-6839EB0A9644Q52716589-6C0AFC61-A1D4-4D55-BE36-072DC8C7EA88
P921
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Reverzna transkriptaza telomeraze
@sh
TERT
@es
Telomerase reverse transcriptase
@en
Telomerase reverse transcriptase
@nl
type
label
Reverzna transkriptaza telomeraze
@sh
TERT
@es
Telomerase reverse transcriptase
@en
Telomerase reverse transcriptase
@nl
altLabel
HEST2
@en
HTERT
@es
TERT
@en
TP2
@en
Telomerasa transcriptasa inversa
@es
telomerase catalytic subunit
@en
telomerase reverse transcriptase
@en
telomerase-associated protein 2
@en
prefLabel
Reverzna transkriptaza telomeraze
@sh
TERT
@es
Telomerase reverse transcriptase
@en
Telomerase reverse transcriptase
@nl
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NP_001180305
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ENSP00000309572
ENSP00000334346
ENSP00000425003
ENSP00000499759