about
Trypanocidal activity of marine natural productsIdentification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaignBiological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathwayConvolutamines I and J, antitrypanosomal alkaloids from the bryozoan Amathia tortusa.Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis.Solving the supply of resveratrol tetramers from Papua New Guinean rainforest anisoptera species that inhibit bacterial type III secretion systems.Development and application of a sensitive, phenotypic, high-throughput image-based assay to identify compound activity against Trypanosoma cruzi amastigotesApproaches to protozoan drug discovery: phenotypic screening.Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.6-Arylpyrazine-2-carboxamides: A New Core for Trypanosoma brucei Inhibitors.Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei.3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.Antiparasitic activity of alkaloids from plant species of Papua New Guinea and Australia.7',8'-Dihydroobolactone, a typanocidal alpha-pyrone from the rainforest tree Cryptocarya obovata.Pseudoceramines A-D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp.Screening a Natural Product-Based Library against Kinetoplastid Parasites.New galloylated flavanonols from the Australian plant Glochidion sumatranum.Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.Antitrypanosomal cyclic polyketide peroxides from the Australian marine sponge Plakortis sp.3-pyridyl inhibitors with novel activity against Trypanosoma cruzi reveal in vitro profiles can aid prediction of putative cytochrome P450 inhibition.Wilsoniamines A and B: novel alkaloids from the temperate Australian bryozoan, Amathia wilsoniDesign, synthesis and biological evaluation of 2-nitroimidazopyrazin-one/-es with antitubercular and antiparasitic activityInvestigation of pyrimidine nucleoside analogues as chemical probes to assess compound effects on the proliferation of Trypanosoma cruzi intracellular parasitesTotal Synthesis of the Antimalarial Ascidian Natural Product AlbopunctatoneThe cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement
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Q27008593-A8054E43-3137-47EB-BB61-AFFA7291CA04Q28485372-DCE41636-A4B6-4066-AB2D-0E6DC6FA7AB5Q28821118-5C09C776-2418-477D-856D-0115B9FF6F8FQ33943104-AD9913DD-03FD-469D-9073-3AB6357C67DAQ34239261-C7934347-C0C9-43ED-A645-871ECA238B2DQ35431956-EAF118C6-BC74-41DD-B965-6D1A3EE8EDB5Q36000826-69A89C82-A0D7-4DE9-BB9D-307DBC468575Q38127474-D194EE30-364E-4C22-AEDD-1EF035689017Q38695331-8F2FE401-31A6-4FF8-9E6B-E1AB18D4ADF0Q38845969-9FD13292-16EA-40E4-9E1C-E7C89ADBE1CEQ38979683-12B8F91D-2BB7-4B61-A73D-1E106845B2EEQ39003623-84D7ED2D-ADD1-4C47-8E47-EA80C6D5B8B4Q39688050-E0912A2F-CFAF-40C4-8A13-8713BF073EF4Q39691505-B62BF673-4D9A-4635-8D56-FF9CE34921ECQ41427000-6D21886F-EB28-4F08-8D5A-41DF4933B9B5Q42796077-6C33B960-BC00-47E8-82BA-D0A2C863750DQ42992869-C62FCF35-34F7-4F58-95A9-FC15AB2AC488Q43264845-DAE33A64-0FBF-4C57-99A1-DB9A6269316BQ51635350-777C5597-F557-4152-AC6A-21125AD32EB8Q52646076-345C607F-757F-43F0-A33E-4101129303C5Q58852802-64A3AE2F-745F-4540-A6BF-BC207357018BQ60949518-8CD028CD-41AF-48C8-82F3-118454B6BD97Q90262574-48B52DA6-FC75-4036-AD8B-F7422DE09B3DQ91738491-B684DDAA-99A7-4035-B554-253E57089796Q93037784-F31A2AAC-4E75-452E-99AF-D665E24DF742
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Melissa Sykes
@en
Melissa Sykes
@nl
type
label
Melissa Sykes
@en
Melissa Sykes
@nl
prefLabel
Melissa Sykes
@en
Melissa Sykes
@nl
P31
P496
0000-0002-9379-9012