about
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewalAdvances in tracking hematopoiesis at the single-cell level.Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification.fastER: a user-friendly tool for ultrafast and robust cell segmentation in large-scale microscopy.Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios.Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors.Prospective identification of hematopoietic lineage choice by deep learning.Software tools for single-cell tracking and quantification of cellular and molecular properties.Network plasticity of pluripotency transcription factors in embryonic stem cells.Mouse and human HSPC immobilization in liquid culture by CD43 or CD44-antibody coating.CSF-1-induced Src signaling can instruct monocytic lineage choice.Lineage marker synchrony in hematopoietic genealogies refutes the PU.1/GATA1 toggle switch paradigm.Inflammatory signals directly instruct PU.1 in HSCs via TNFSingle-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewalWnt to notch relay signaling induces definitive hematopoiesisInductive and Selective Effects of GSK3 and MEK Inhibition on Nanog Heterogeneity in Embryonic Stem CellsAutomated Microfluidic System for Dynamic Stimulation and Tracking of Single CellsUnderstanding cell fate control by continuous single-cell quantificationAsymmetric lysosome inheritance predicts activation of haematopoietic stem cells
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Dirk Loeffler
@en
Dirk Loeffler
@nl
type
label
Dirk Loeffler
@en
Dirk Loeffler
@nl
prefLabel
Dirk Loeffler
@en
Dirk Loeffler
@nl
P31
P496
0000-0001-9870-0088