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Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning.Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytesA genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identityNeuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brainPharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytesA transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitorsHuman Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data GenerationA novel component of the ubiquitin pathway, ubiquitin carboxyl extension protein 1 is overexpressed in prostate cancer.Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivativesFrom transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.Identification of specific pluripotent stem cell death--inducing small molecules by chemical screening.Extensive transcriptional regulation of chromatin modifiers during human neurodevelopment.Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells.Corrigendum: Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca(2+) release channel.Does the coronary risk factor low density lipoprotein alter growth and signaling in vascular smooth muscle cells?Inhibition of the Low Density Lipoprotein-Induced Vascular Smooth Muscle Cell Growth by PPARgamma Ligands.Cardiac specific differentiation of mouse embryonic stem cells.Lineage-specific regulation of epigenetic modifier genes in human liver and brainToxicogenomics directory of chemically exposed human hepatocytes.Embryonic stem cells: a promising tool for cell replacement therapy.Trapping of growth factors by catechins: a possible therapeutical target for prevention of proliferative diseases.Embryonic stem cells for basic research and potential clinical applications in cardiology.Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cellsIdentification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration.Dietary small molecules and large-scale gene expression studies: an experimental approach for understanding their beneficial effects on the development of malignant and non-malignant proliferative diseases.Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca(2+) release channel.The FunGenES consortium: functional genomics in engineered embryonic stem cells.Cardiovascular genomics: a current overview of in vivo and in vitro studies.Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants.A chemical genetics approach for specific differentiation of stem cells to somatic cells: a new promising therapeutical approach.Human ES cell derived cardiomyocytes for cell replacement therapy: a current update.Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals.Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O-gallate, quercetin and curcumin against cancer and cardiovascular diseases.Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells.Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assayDesign principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells.Specific gene signatures and pathways in mesodermal cells and their derivatives derived from embryonic stem cells.Current status of human pluripotent stem cell based in vitro toxicity tests.Unique metabolic features of stem cells, cardiomyocytes, and their progenitors.
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description
researcher (ORCID 0000-0003-3054-225X)
@en
wetenschapper
@nl
name
Agapios Sachinidis
@en
Agapios Sachinidis
@nl
type
label
Agapios Sachinidis
@en
Agapios Sachinidis
@nl
prefLabel
Agapios Sachinidis
@en
Agapios Sachinidis
@nl
P31
P496
0000-0003-3054-225X