about
P688
Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastomaCombined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable diseaseAurora-A overexpression in mouse liver causes p53-dependent premitotic arrest during liver regenerationAurora-A kinase is essential for bipolar spindle formation and early developmentChfr is required for tumor suppression and Aurora A regulationAurora-A is a critical regulator of microtubule assembly and nuclear activity in mouse oocytes, fertilized eggs, and early embryosConditional Aurora A deficiency differentially affects early mouse embryo patterningAn essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamicsAurora kinase-A regulates microtubule organizing center (MTOC) localization, chromosome dynamics, and histone-H3 phosphorylation in mouse oocytesNDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitmentA novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulatorsAurora kinase-A deficiency during skin development impairs cell division and stratificationAurora A is essential for early embryonic development and tumor suppressionTargeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality
P921
Q24296639-9AC35F38-AA3B-4733-846B-9448B717EE0CQ24310764-A363153A-0EBF-401B-AB60-DCDB7D85766CQ28116205-52DA5506-D3B7-4A3D-83DC-11838D72965DQ28506140-ECAFBCAD-6993-422C-AF6B-9FA9F7DFF6C1Q28510913-F32FCA47-C099-4DBB-8FE3-D79A87E8CB58Q28512021-2FAF564B-3530-4842-A7F7-DC2B0FC41B2EQ28584840-B107D74E-D038-4F0B-9DD3-07CEE5DBD65CQ28585404-58B74843-C504-400A-9A55-5BD2FFBBB20EQ28586374-027BFC09-F4A2-40FD-87AD-314BACCA05EFQ28587157-034F5210-CEC7-455E-8549-5A38E63CFEBFQ28589729-78C60BE2-FCD1-40B6-A7BF-2E1BD48C6E4DQ28590357-56A24C9C-804D-45C7-9665-31C7C9FE4B11Q28590685-66A42269-F994-4270-860F-EE9BFDD85C13Q28594290-20E37969-3A1E-44C8-B31E-C93167301904
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Aurora kinase A
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Aurora kinase A
@en
type
label
Aurora kinase A
@en
altLabel
ARK-1
@en
Aurka
@en
aurora 2
@en
aurora A
@en
aurora family kinase 1
@en
aurora kinase A
@en
aurora-related kinase 1
@en
aurora/IPL1-related kinase 1
@en
ipl1- and aurora-related kinase 1
@en
serine/threonine kinase 6
@en
prefLabel
Aurora kinase A
@en
P527
P637
P638
P680
P681
P682
P705
P352
P279
P31
P352
P527
P637
NP_001278114
XP_006499138
P638
P680
P681
P682
P702
P703
P705
ENSMUSP00000028997
ENSMUSP00000104767
ENSMUSP00000104768