about
sameAs
P688
The Batten disease gene product (CLN3p) is a Golgi integral membrane proteinIntracellular trafficking of the JNCL protein CLN3Studies of membrane association of CLN3 proteinTissue expression and subcellular localization of CLN3, the Batten disease proteinDefective intracellular transport of CLN3 is the molecular basis of Batten disease (JNCL)CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cellsCLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles: new clues to Batten diseaseElevated lysosomal pH in neuronal ceroid lipofuscinoses (NCLs)Defective lysosomal arginine transport in juvenile Batten diseaseA galactosylceramide binding domain is involved in trafficking of CLN3 from Golgi to rafts via recycling endosomesMembrane topology of CLN3, the protein underlying Batten diseaseNeuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartmentsInterconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathwayBiosynthesis and intracellular targeting of the CLN3 protein defective in Batten diseaseNovel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteinsCLN3p impacts galactosylceramide transport, raft morphology, and lipid contentA novel interaction of CLN3 with nonmuscle myosin-IIB and defects in cell motility of Cln3(-/-) cellsOsmotic stress changes the expression and subcellular localization of the Batten disease protein CLN3.AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif.Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease.Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells.A novel role of the Batten disease gene CLN3: association with BMP synthesis.Loss of the Batten disease gene CLN3 prevents exit from the TGN of the mannose 6-phosphate receptor.
P921
Q22001475-B1B28E8E-D201-43FD-8599-0BE0AF90AA22Q22009144-E97841CA-F7C4-41E0-BF40-F30A049891B0Q22009145-655FDB53-1E97-42CE-A69E-6A6BF1ADAD11Q22009146-0393EC1D-3853-456B-BDC7-B13AC97D8BE7Q22010059-899EF62D-E103-4D73-942D-150F2C5E553AQ22254722-569B5CAB-983B-41C5-856C-E1573BAD31C2Q24291761-9D4D86F8-28C4-4B0E-8A57-B1699F83062FQ24291928-7EF6C4EA-E124-44EC-9A29-99BCDCABEFF6Q24292865-6869936C-D32F-4758-8264-554853B73703Q24298716-671CA78F-7FFB-4BC1-8F82-F31180AC1B86Q24300266-8B1A1F61-1483-4EE3-9FBD-33EEA8131B13Q24302244-C0DE99FE-1D2A-4A36-A9D7-29A7451794D9Q24306585-95265A63-AA75-4104-A8DC-866D3930211BQ24310339-A720F089-967D-4131-B4AB-B4AA9F8E144CQ28115540-3F83E809-44E2-404D-BCEC-E6DB31C1CC89Q28271390-E863859B-4200-4345-8075-C8C698CF0A3AQ34014206-9ACB9F46-6B99-4E07-95F8-C25399724C10Q34805162-3CB5FC82-1B1D-49CD-85DE-7E10103CA5C6Q40480798-52B7EC54-F6AE-4E5B-B95B-67B2A081A49DQ40611905-519DA678-8F3A-442A-9530-F97B30633EABQ40648630-C08762BD-CDAF-4DB3-B5EE-65D433ED8C92Q43080212-561BDBE1-2670-4B5D-B5E3-71F63B2B5769Q46346855-9F666C41-F90A-4920-8DAA-9BE1B1DA61B4
P921
description
Protein
@de
mammalian protein found in Homo sapiens
@en
protein
@br
protein
@id
protein
@sv
proteinë
@sq
proteïne in CLN3
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
CLN3 lysosomal/endosomal transmembrane protein, battenin
@en
CLN3
@br
CLN3
@en-ca
CLN3
@en-gb
CLN3
@fr
CLN3
@nl
type
label
CLN3 lysosomal/endosomal transmembrane protein, battenin
@en
CLN3
@br
CLN3
@en-ca
CLN3
@en-gb
CLN3
@fr
CLN3
@nl
altLabel
CLN3
@en
CLN3, battenin
@en
Protein CLN3
@en
batten disease protein
@en
battenin
@en
ceroid-lipofuscinosis, neuronal 3
@en
prefLabel
CLN3 lysosomal/endosomal transmembrane protein, battenin
@en
CLN3
@br
CLN3
@en-ca
CLN3
@en-gb
CLN3
@fr
CLN3
@nl
P361
P637
P681
P682
P705
P352
P31
P352
P361
P637
NP_001035897
NP_001273033
NP_001273034
NP_001273038
NP_001273039
P681
P682
P702
P703
P705
ENSP00000329171
ENSP00000347660
ENSP00000350457
ENSP00000350523
ENSP00000353073
ENSP00000353116
ENSP00000379014
ENSP00000454229
ENSP00000454466
ENSP00000454680
P7260
2.A.57.5.8