sameAs
Dual anti-oxidative effects of fraxetin isolated from Fraxinus rhinchophylla.Fraxetin Induces Heme Oxygenase-1 Expression by Activation of Akt/Nrf2 or AMP-activated Protein Kinase α/Nrf2 Pathway in HaCaT Cells.Antitumor and antimetastatic actions of dihydroxycoumarins (esculetin or fraxetin) through the inhibition of M2 macrophage differentiation in tumor-associated macrophages and/or G1 arrest in tumor cells.Bone morphogenetic protein-2 and -4 (BMP-2 and -4) mediates fraxetin-induced maturation and differentiation in human osteoblast-like cell lines.Fraxetin prevents rotenone-induced apoptosis by induction of endogenous glutathione in human neuroblastoma cells.Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells.Antibacterial mechanism of fraxetin against Staphylococcus aureus.The hepatoprotective effect of fraxetin on carbon tetrachloride induced hepatic fibrosis by antioxidative activities in rats.Antioxidant activity of Fraxetin: in vivo and ex vivo parameters in normal situation versus induced stress.Effect of fraxetin and myricetin on rotenone-induced cytotoxicity in SH-SY5Y cells: comparison with N-acetylcysteine.[Relationship between the inhibitory effect of fraxetin on breast cancer and estrogen signaling pathway].Effect of fraxetin on antioxidant defense and stress proteins in human neuroblastoma cell model of rotenone neurotoxicity. Comparative study with myricetin and N-acetylcysteine.Fraxetin and ethyl acetate extract from Lawsonia inermis L. ameliorate oxidative stress in P. berghei infected mice by augmenting antioxidant defence system.Effect of fraxetin on proliferation and apoptosis in breast cancer cells.Antimicrobial Effects of 7,8-Dihydroxy-6-Methoxycoumarin and 7-Hydroxy-6-Methoxycoumarin Analogues against Foodborne Pathogens and the Antimicrobial Mechanisms Associated with Membrane Permeability.The therapeutic effect of fraxetin on ethanol-induced hepatic fibrosis by enhancing ethanol metabolism, inhibiting oxidative stress and modulating inflammatory mediators in rats.Antihyperglycemic effect of fraxetin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats.Biosynthesis of redox-active metabolites in response to iron deficiency in plants.Scopoletin 8-Hydroxylase-Mediated Fraxetin Production is Crucial for Iron Mobilization.Simultaneous determination of fraxin and its metabolite, fraxetin, in rat plasma by liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study.Simultaneous Determination of Aesculin, Aesculetin, Fraxetin, Fraxin and Polydatin in Beagle Dog Plasma by UPLC-ESI-MS/MS and Its Application in a Pharmacokinetic Study after Oral Administration Extracts of LIsolation and Purification of Bioactive Compounds from the Stem Bark ofThe Efflux Mechanism of Fraxetin--Glucuronides in UGT1A9-Transfected HeLa Cells: Identification of Multidrug Resistance-Associated Proteins 3 and 4 (MRP3/4) as the Important ContributorsModifications on antioxidant capacity and lipid peroxidation in mice under fraxetin treatmentIdentification and characterization of human UDP-glucuronosyltransferases responsible for the glucuronidation of fraxetinInhibition of osteoclastogenesis for periprosthetic osteolysis therapy through the suppression of p38 signaling by fraxetin
P921
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P921
description
chemesch Verbindung
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chemical compound
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chemical compound
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chemical compound
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chemická sloučenina
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chemická zlúčenina
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chemiese verbinding
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chemische Verbindung
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chemische Verbindung
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chemische verbinding
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name
Fraksetin
@sh
Fraksetin
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Fraxetin
@de
Fraxetin
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fraxetin
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fraxetina
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フラキセチン
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type
label
Fraksetin
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Fraksetin
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Fraxetin
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Fraxetin
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fraxetin
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fraxetina
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フラキセチン
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prefLabel
Fraksetin
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Fraksetin
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Fraxetin
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Fraxetin
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fraxetin
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fraxetina
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フラキセチン
@ja
P4964
P6689
P592
P6366
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P117
P2064
P2067
208.037173
P231
P232
P233
COC1=C(C(=C2C(=C1)C=CC(=O)O2)O)O
P234
1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3
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HAVWRBANWNTOJX-UHFFFAOYSA-N
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100.008.525
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DTXSID00205992
P4964
splash10-0006-0900000000-c9b821d885fe7313627a
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P592
CHEMBL54909
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2777287617
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CD3GD44O3K