2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine
Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STINGStructure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAAcGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA.The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling
P921
2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine
@en
GMP-AMP cyclique
@fr
type
label
2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine
@en
GMP-AMP cyclique
@fr
altLabel
Cyclic guanosine monophosphate-adenosine monophosphate
@en
cyclic GMP-AMP
@en
cyclic [G(2',5')pA(3',5')p]
@en
prefLabel
2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine
@en
GMP-AMP cyclique
@fr
P638
P6366
P661
P662
P683
P2017
C1[C@@H]2[C@H]([C@H]([C@@H](O2 ...... 7=C6N=CN=C7N)O)OP(=O)(O1)O)O)O
P2067
P231
1441190-66-4
P233
C1C2C(C(C(O2)N3C=NC4=C3NC(=NC4 ...... 7=C6N=CN=C7N)O)OP(=O)(O1)O)O)O
P234
1S/C20H24N10O13P2/c21-14-8-15( ...... ,10-,11-,12-,13-,18-,19-/m1/s1
P235
XRILCFTWUCUKJR-INFSMZHSSA-N
P274
C₂₀H₂₄N₁₀O₁₃P₂
P6366
2777002656
P638
P652
552Y49K43E