Radiocarbon dating of the human eye lens crystallines reveal proteins without carbon turnover throughout life
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Eye lens radiocarbon reveals centuries of longevity in the Greenland shark (Somniosus microcephalus)14C BOMB-PULSE DATING AND STABLE ISOTOPE ANALYSIS FOR GROWTH RATE AND DIETARY INFORMATION IN BREAST CANCER?No turnover in lens lipids for the entire human lifespanBomb-curve radiocarbon measurement of recent biologic tissues and applications to wildlife forensics and stable isotope (paleo)ecologyBomb-pulse 14C analysis combined with 13C and 15N measurements in blood serum from residents of Malmö, SwedenBomb Pulse BiologyRacemisation and human cataract. D-Ser, D-Asp/Asn and D-Thr are higher in the lifelong proteins of cataract lenses than in age-matched normal lensesThe stratified syncytium of the vertebrate lens.Protein aging: truncation of aquaporin 0 in human lens regions is a continuous age-dependent process.Age-dependent deamidation of lifelong proteins in the human lens.Non-invasive bleaching of the human lens by femtosecond laser photolysis.Large-scale binding of α-crystallin to cell membranes of aged normal human lenses: a phenomenon that can be induced by mild thermal stressSphingolipid distribution changes with age in the human lens.Biophysical chemistry of the ageing eye lens.Beta-1 integrin is important for the structural maintenance and homeostasis of differentiating fiber cells.Are ancient proteins responsible for the age-related decline in health and fitness?Anaerobic vs aerobic pathways of carbonyl and oxidant stress in human lens and skin during aging and in diabetes: A comparative analysisIdentification of long-lived proteins retained in cells undergoing repeated asymmetric divisions.A serine-type protease activity of human lens βA3-crystallin is responsible for its autodegradation.α- and β-crystallins modulate the head group order of human lens membranes during aging.Epigenetic regulation of αA-crystallin in high myopia-induced dark nuclear cataractLipid domains in intact fiber-cell plasma membranes isolated from cortical and nuclear regions of human eye lenses of donors from different age groups.Spontaneous cyclization of polypeptides with a penultimate Asp, Asn or isoAsp at the N-terminus and implications for cleavage by aminopeptidase.Understanding the α-crystallin cell membrane conjunction.MALDI Imaging Mass Spectrometry Spatially Maps Age-Related Deamidation and Truncation of Human Lens Aquaporin-0.Amounts of phospholipids and cholesterol in lipid domains formed in intact lens membranes: Methodology development and its application to studies of porcine lens membranesDegradation of an old human protein: age-dependent cleavage of γS-crystallin generates a peptide that binds to cell membranesCarbon turnover in the water-soluble protein of the adult human lens.Instability of the cellular lipidome with age.Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?High-resolution mass spectrometry analysis of protein oxidations and resultant loss of functionTransglutaminse 2 and EGGL, the protein cross-link formed by transglutaminse 2, as therapeutic targets for disabilities of old age.Functions of the intermediate filament cytoskeleton in the eye lens.Old proteins and the Achilles heel of mass spectrometry. The role of proteomics in the etiology of human cataract.Radiocarbon analysis of human remains: a review of forensic applications.Photosensitizing Activity of Endogenous Eye Lens Chromophores: An Attempt to Unravel Their Contributions to Photo-Aging and Cataract Disease.Structural and functional properties of NH(2)-terminal domain, core domain, and COOH-terminal extension of αA- and αB-crystallins.Overview of the Lens.The etiology of human age-related cataract. Proteins don't last forever
P2860
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P2860
Radiocarbon dating of the human eye lens crystallines reveal proteins without carbon turnover throughout life
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Radiocarbon dating of the huma ...... arbon turnover throughout life
@ast
Radiocarbon dating of the huma ...... arbon turnover throughout life
@en
Radiocarbon dating of the huma ...... arbon turnover throughout life
@en-gb
Radiocarbon dating of the huma ...... arbon turnover throughout life
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type
label
Radiocarbon dating of the huma ...... arbon turnover throughout life
@ast
Radiocarbon dating of the huma ...... arbon turnover throughout life
@en
Radiocarbon dating of the huma ...... arbon turnover throughout life
@en-gb
Radiocarbon dating of the huma ...... arbon turnover throughout life
@nl
altLabel
Radiocarbon Dating of the Huma ...... arbon Turnover throughout Life
@en
prefLabel
Radiocarbon dating of the huma ...... arbon turnover throughout life
@ast
Radiocarbon dating of the huma ...... arbon turnover throughout life
@en
Radiocarbon dating of the huma ...... arbon turnover throughout life
@en-gb
Radiocarbon dating of the huma ...... arbon turnover throughout life
@nl
P2093
P2860
P3181
P1433
P1476
Radiocarbon dating of the huma ...... arbon turnover throughout life
@en
P2093
Henrik Kjeldsen
Jan Heinemeier
Niels Lynnerup
Steffen Heegaard
P2860
P3181
P356
10.1371/JOURNAL.PONE.0001529
P407
P577
2008-01-01T00:00:00Z