about
Cell division cycle 42Parkin RBR E3 ubiquitin protein ligaseUbiquitin protein ligase E3AVon Hippel-Lindau tumor suppressorCell division cycle 42F-box and leucine-rich repeat protein 3Ring finger protein 14Ring finger protein 6SH3 domain containing ring finger 2Checkpoint with forkhead and ring finger domainsSNF2 histone linker PHD RING helicaseChromosome 18 open reading frame 25F-box protein 44Tripartite motif containing 25Ubiquitin like with PHD and ring finger domains 1FA complementation group FNCCRP1, F-box associated domain containingF-box protein 27F-box protein 30F-box protein 17F-box protein 6F-box protein 40F-box and leucine rich repeat protein 6F-box and leucine rich repeat protein 8Ariadne RBR E3 ubiquitin protein ligase 2Cullin 1Cullin 5Ariadne RBR E3 ubiquitin protein ligase 1Ubiquitin conjugating enzyme E2 OInterferon regulatory factor 2 binding protein 1Interferon regulatory factor 2 binding protein likeTripartite motif containing 32WW domain containing E3 ubiquitin protein ligase 2Anaphase promoting complex subunit 4Ring finger protein 144BMediator complex subunit 7Ring finger protein 41WW domain containing E3 ubiquitin protein ligase 1NEDD4 E3 ubiquitin protein ligaseMediator complex subunit 31
P680
Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signalingA HECT domain E3 enzyme assembles novel polyubiquitin chainsU box proteins as a new family of ubiquitin-protein ligasesThe ubiquitin-protein ligase Itch regulates p73 stabilityZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPaseIdentification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arraysPOSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domainThe RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradationTRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodiesA ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrateASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexesInteraction of the Salmonella Typhimurium effector protein SopB with host cell Cdc42 is involved in intracellular replicationF-box and leucine-rich repeat protein 22 is a cardiac-enriched F-box protein that regulates sarcomeric protein turnover and is essential for maintenance of contractile function in vivoPolycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)E3 ubiquitin ligase RNF126 promotes cancer cell proliferation by targeting the tumor suppressor p21 for ubiquitin-mediated degradationMARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphologyCbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradationTranscription-independent ARF regulation in oncogenic stress-mediated p53 responsesCircadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligaseRas regulates assembly of mitogenic signalling complexes through the effector protein IMPNIRF is a ubiquitin ligase that is capable of ubiquitinating PCNP, a PEST-containing nuclear proteinCYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligasesRoquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOSFANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCLThe HLA-DRalpha chain is modified by polyubiquitinationA family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligaseTRIP12 functions as an E3 ubiquitin ligase of APP-BP1Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domainsAxin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigenMdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytesThe HECT domain of TRIP12 ubiquitinates substrates of the ubiquitin fusion degradation pathwayMHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulationRNF38 encodes a nuclear ubiquitin protein ligase that modifies p53Endoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligaseRoquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responsesE3 ubiquitin ligase COP1 regulates the stability and functions of MTA1Protein microarray characterization of the S-nitrosoproteome
P921
Q1198053-15078588-EE5C-4A7D-A1E4-D89BB693FD75Q14864264-18651854-6B13-43E6-890E-8E7E1BE2D1E7Q14864264-F7914F88-B3B4-4268-B984-29639F74CDF0Q14878332-F1A331D4-7FCD-48DF-9B77-718B89615A48Q14905477-62B4D757-D334-4B67-8E17-7698C2A4BB03Q15311709-ED2FE5BF-3B42-4A69-ADED-6CF8957C2B13Q15323488-D290ABF2-BF46-4509-92DF-66D342BA7632Q21097359-442903BC-2404-455C-A063-E1811F06AAE8Q21097370-3214443A-6845-4397-B7E8-E188897A4880Q21097370-B03CC548-3746-4070-9DB6-893C51A2584FQ21100407-6C181958-2208-4AD8-A966-DB1AA82BAB0CQ21100407-DD14623A-C6FF-46D2-98DB-BF0DCA329ED2Q21100748-F52478A7-1EED-4531-B2DC-5C249EF15F3EQ21100915-09EE769F-1C8F-4333-B05C-1F69A0A93377Q21100915-52591423-B361-464A-9481-5637A0DF8143Q21100951-4BDC4A77-2306-4EA7-BE3E-4C0F99CA6F22Q21100961-00B201FE-A36B-4C95-B91B-90663C01EF5AQ21101064-ADAF2925-6051-4EC5-B5EF-604992233E01Q21101064-E1DAFA3B-0CDD-487D-B737-40837F1A435BQ21101117-C8C70B8F-73ED-49BB-9627-D98034284D03Q21101318-3928C971-FEA4-4940-9B55-46CA9AB1B8FBQ21101348-FC30BCB4-7EB3-45DE-AA5E-212B2F809570Q21101361-A784F8C0-BF50-4D81-9390-F3BFD97E4F40Q21101362-0F537D3A-5540-43FC-A74A-C9D86574833BQ21101368-9B81BEB9-414B-4216-BC7B-8B1E8D676F1AQ21101374-7F60D6F3-B64B-43AA-B215-18B27B759041Q21101376-DE6F927B-FF5D-4C2B-AA69-14B17D760D22Q21101421-1062D331-6BCF-4C10-8F3B-7632F20E3052Q21101429-3F806DCC-D004-46AD-8FCE-E295AB079633Q21101919-2C03AA31-088A-4F6D-9122-75F64C77CCF8Q21101946-D49C3EB6-C303-4BD1-995B-965393F0FFAFQ21101987-F7CEF68B-96F9-4DC2-B309-D8CE4408A90DQ21102006-E38127D1-F163-4F89-ABD8-A0210D0459DFQ21102673-11DC7C0E-E3E0-4B31-A17B-B18CFC9CC281Q21102673-CAAD2260-7511-4286-A7D2-7C57C3F8757FQ21103394-7C1EDB44-0A78-4651-B3A7-E32AB12D43B6Q21103409-10CC63FA-E8AC-4436-9ED8-7D13643C4012Q21104807-3E06DCA0-94B7-4A20-B95C-BE5BB5A42014Q21104807-D9FCDB16-A8AB-4556-B2D6-1EEBD0E1F9DCQ21105130-B943BC78-88A3-48D9-B95A-017D44FD6653
P680
Q21144354-D783FA47-EE51-428E-9C22-4C439BA02E17Q24291047-8A8559FC-13BC-4113-8688-233E54177613Q24291397-F05CF9F9-9BD5-4464-82C0-B10684785D40Q24293071-4EACF6B4-D1E8-432E-B391-56496F6F7C0CQ24293429-87B3078B-9171-42C8-9295-AAFA2436412FQ24294183-4254CFA1-1E2B-4E55-A0C8-BE578752B75CQ24294740-FFF7D2C9-AE2C-4108-ABD5-4192A54C7B9BQ24294989-21DF5C15-50E6-48FD-B8F2-73888BEDB128Q24296382-A8EA9786-0D64-412C-94E6-53847334F243Q24297635-4480F4EF-2244-4028-8EDD-A73FEC99F5AFQ24297841-D37C56A0-11AE-4717-BAFB-30BF21C949E9Q24298029-35FD83CF-4D29-4E9A-BC0A-7C8437363E6BQ24298563-60C8F82C-541F-4B18-B041-B70F16466734Q24299323-85219CE7-5800-488A-9C04-7AC76DBCA1B7Q24299616-B3645352-DE76-4D26-9775-01271C13061DQ24299938-5AF944AC-903C-4E97-B791-C8D786F0A54EQ24300832-770BEC1D-F095-4ECC-A87F-DE9B56389D3BQ24301400-9052FA55-4056-42E3-B3C4-5512BCF4016BQ24301836-969BA699-2FAB-42E8-B9D8-FC911F7DD35DQ24304122-60E366EC-C357-4897-AAF7-08902C8E9183Q24305011-E4016050-0875-4B28-A67E-F8A77A18FF0FQ24306164-5104CD19-8DD9-4037-9CFE-52F27890D9A4Q24310116-3BA9FA81-CA5B-4D39-BC50-D99374528B53Q24310725-C61831C2-7FB7-477F-ABD4-CABF26C75EDAQ24312445-8DE74C00-4B4E-477C-B42E-AA17406F9844Q24312515-63A41E1F-DE30-4FAC-8D15-D0051D5476E6Q24313174-84F74E34-5382-4ABD-9C48-7B694E5BA7D8Q24313441-56696288-5C32-452F-A2B7-008F6886ED8AQ24315623-30C879C0-8A0A-4C94-AD0E-6B9ABE72299FQ24315751-7F23EB8D-741E-47BA-99AC-67AD3C37F55CQ24315880-0127ACA1-6A8F-48C7-9005-55D2F7ADD8F7Q24316484-DDC41F9F-08AF-4125-9825-7E5104B93E12Q24317219-1C6742E2-E4E5-4A01-B5D3-5514969A0E5EQ24317229-DF25B9C8-4074-40E9-8458-23F979FCDBC8Q24318499-8F950A09-1827-49B9-97D1-DC479C51C4D1Q24319062-5C5365D0-54B7-48FA-911A-6D4810561B82Q24320293-4E2627CE-3A5B-4ADC-B30C-349C4E449F80Q24321870-C585335E-2188-41CA-997A-D937DFE6EE64Q24322010-6092E606-A617-43C6-9EEF-2B8CE20EAC1FQ24337911-DA459A71-B6F1-4768-8684-C4CE097DD71C
P921
description
Catalysis of the transfer of u ...... nkage is an amide bond: an iso
@en
biologisch proces
@nl
name
ubiquitin protein ligase activity
@en
type
label
ubiquitin protein ligase activity
@en
altLabel
GO:0061630
@en
protein ubiquitination activity
@en
ubiquitin ligase activity
@en
prefLabel
ubiquitin protein ligase activity
@en
P686
P2888
P686
GO:0061630