about
P688
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cellsDynamin-like protein 1 at the Golgi complex: a novel component of the sorting/targeting machinery en route to the plasma membraneThe dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamicsMembrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerizationFis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesisThe mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathwaysHuman MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fissionThe BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanismsAn actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2Identification and functional characterization of a novel human protein highly related to the yeast dynamin-like GTPase Vps1pThe novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cellsMff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cellsAdaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fissionMAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fissionInterchangeable adaptors regulate mitochondrial dynamin assembly for membrane scissionSpatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosisPhosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamicsParkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexesInteraction with the effector dynamin-related protein 1 (Drp1) is an ancient function of Rab32 subfamily proteinsSignal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fissionA novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cellsBiallelic Mutations in DNM1L are Associated with a Slowly Progressive Infantile Encephalopathy.Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance.Mutations in DNM1L, as in OPA1, result indominant optic atrophy despite opposite effectson mitochondrial fusion and fission.DNM1L-related encephalopathy in infancy with Leigh syndrome-like phenotype and suppression-burst.Phosphorylation of dynamin-related protein 1 at Ser616 regulates mitochondrial fission and is involved in mitochondrial calcium uniporter-mediated neutrophil polarization and chemotaxis.A novel de novo dominant negative mutation in DNM1L impairs mitochondrial fission and presents as childhood epileptic encephalopathy.Postnatal microcephaly and pain insensitivity due to a de novo heterozygous DNM1L mutation causing impaired mitochondrial fission and functionATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects
P921
Q24291591-F5973CC2-9123-4C62-A69F-330F880CE12EQ24294520-DAF3E136-B28B-450C-9018-8F4EFBBD8DD0Q24296804-936EDABB-C11A-4976-8E4F-0DF7F03FDAF1Q24298316-CBCF6D88-D473-4126-8DF0-E1BABC075CA7Q24300125-BAD5DD89-E6FC-4E56-9270-C5F9053ABF92Q24301650-75E25B1B-6E01-4563-805C-8D2B99081F25Q24302411-7D6D0DA7-70C6-43B7-A08C-A52565B4996CQ24307740-AF29E341-147B-4BB4-B941-07D8AC5117E3Q24309355-C950BE2F-D167-4A5A-9274-0C24B0DEB0D5Q24311384-50CF6BBF-23AC-4AB4-9FE4-83EB5D249E39Q24312112-0189B1F6-514B-4C50-A163-A87A44309731Q24312865-D8752FC8-1D49-4697-95DD-F34CD709B500Q24315625-95D94166-5BF4-45F6-899A-E3B98738CFEAQ24315659-CF2435D1-0111-4357-A3FA-611A29614FCFQ24320327-A5B692DA-0C23-488A-9B39-7552DBF1E2B3Q24320331-A0426C18-108E-4CE6-ADFD-02996BAEFBC8Q24337363-8DB9EF3B-07C8-492B-A97B-63629D84552DQ24337576-01CE4C53-E2D9-4363-B7A4-A7525B14D386Q24338713-9442644B-1087-4E52-AED9-AEC10570DC5DQ28115112-98CC6125-C79E-49A1-9351-49369F2E1CE7Q28115441-9E7C00D2-20DC-415B-82B7-1AE92E9319C9Q28115520-A6B537D2-08C3-44CD-9728-935D97B07A0FQ28117314-77254CCB-7737-4CB4-89C7-96AFD6EDA398Q42135472-1AFFE28A-4D2E-43E5-A7A8-DD41A44C9768Q47172200-05150E0F-630B-401B-95C6-23D8555DA8F9Q47713821-1446D8E9-F220-4BC0-945C-E94E3AA459D7Q47903491-2BE36138-D372-4BBF-A304-BA84244A4787Q51067256-05E42D8B-AB8A-4C31-B555-F679C2A59111Q52137131-D0F3F39A-0879-4E17-87E4-FFC2862D55FDQ52162414-FAC47AD4-B9E8-4579-978D-9301559EFBE6Q64120447-4FF0090C-1E0E-4C10-8274-E29907CB4B8B
P921
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Dynamin 1 like
@en
Dynamin 1 like
@nl
type
label
Dynamin 1 like
@en
Dynamin 1 like
@nl
altLabel
DNM1L
@en
DVLP
@en
Dnm1p/Vps1p-like protein
@en
Dymple
@en
Dynamin-like protein
@en
HdynIV
@en
dynamin family member proline-rich carboxyl-terminal domain less
@en
dynamin-1-like protein
@en
dynamin-like protein 4
@en
dynamin-like protein IV
@en
prefLabel
Dynamin 1 like
@en
Dynamin 1 like
@nl
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NP_001265392
NP_001265393
NP_001265394
NP_001265395
NP_001317309
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ENSP00000266481
ENSP00000350948
ENSP00000370388
ENSP00000390090
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ENSP00000404160
ENSP00000415131
ENSP00000447013
ENSP00000447788
ENSP00000447845