P688
A cellular defense pathway regulating transcription through poly(ADP-ribosyl)ation in response to DNA damagePARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformationA novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responsesBAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivationSIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress.Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replicationA role of DNA-PK for the metabolic gene regulation in response to insulinDeficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative diseaseTxk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cellsPARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repairWDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA DamageTimeless Interacts with PARP-1 to Promote Homologous Recombination RepairPhosphorylation of p53 by TAF1 inactivates p53-dependent transcription in the DNA damage responseADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodelingTNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1Human nuclear NAD+ ADP-ribosyltransferase(polymerizing): organization of the geneHPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation ActivityA role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expressionTrp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signalingSerine ADP-Ribosylation Depends on HPF1XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53.Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro.Role of glutamic acid 988 of human poly-ADP-ribose polymerase in polymer formation. Evidence for active site similarities to the ADP-ribosylating toxins.Identification of the ADP-ribosylation sites in the PARP-1 automodification domain: analysis and implications.Nuclear cGAS suppresses DNA repair and promotes tumorigenesis[Poly(ADP-Ribose) polymerase 1 as a key regulator of DNA repair]
P921
Q50253186-540ED604-4EE9-4AF5-A44E-3998242F281FQ50253197-8229D87C-247C-4FA6-9C44-BE8885BEC8C6Q50257954-F3104DFB-8331-4BA1-9F13-14ACA3364883Q50268698-8E586D67-5BCD-4885-912A-1F8FA5DA0720Q50290138-CF0A30AC-2FC6-4A68-8361-BC4BBFB2A64AQ50290139-65522324-E0E1-4C6A-B9C8-41707D276020Q50296429-4801CF3A-FF55-4D41-A52E-9CA25CDAF2E6Q50296431-5A9CC3C2-52AE-440E-8559-C49C4B0DA6BB
P527
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Poly(ADP-ribose) polymerase 1
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
PARP1
@cy
PARP1
@gl
PARP1
@uk
Poly
@nl
Poly(ADP-ribose) polymerase 1
@en
Poly(ADP-ribose) polymérase 1
@fr
Poly(ADP-ribose)-Polymerase 1
@de
type
label
PARP1
@cy
PARP1
@gl
PARP1
@uk
Poly
@nl
Poly(ADP-ribose) polymerase 1
@en
Poly(ADP-ribose) polymérase 1
@fr
Poly(ADP-ribose)-Polymerase 1
@de
altLabel
ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
@en
ADP-ribosyltransferase NAD(+)
@en
ADP-ribosyltransferase diphtheria toxin-like 1
@en
ADPRT 1
@en
ARTD1
@en
DNA ADP-ribosyltransferase PARP1
@en
NAD(+) ADP-ribosyltransferase 1
@en
PARP1
@en
poly (ADP-ribose) polymerase family, member 1
@en
poly [ADP-ribose] polymerase 1
@en
prefLabel
PARP1
@cy
PARP1
@gl
PARP1
@uk
Poly
@nl
Poly(ADP-ribose) polymerase 1
@en
Poly(ADP-ribose) polymérase 1
@fr
Poly(ADP-ribose)-Polymerase 1
@de
P361
P527
P638
P680
P681
P682
P705
P352
P6366
P637
P31
P352
P361
P527
P6366
2778480876
P637
P638
P680
P681
P682
P702
P703
P705
ENSP00000355755
ENSP00000355757
ENSP00000355759
ENSP00000485852