P688
The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2The sialoadhesin CD33 is a myeloid-specific inhibitory receptorEngagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cellsMicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic outputIsolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cellsCharacterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells.Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling.FRMD4A-cytohesin signaling modulates the cellular release of tau.
P921
Q22009405-FA66B3B1-25DD-4634-9BD1-8AD6285FD821Q22010780-2AB736E5-2B17-41E9-B921-207D124C03CFQ22010987-5ADD75BD-EE0E-4172-8494-E7AF027FD3D5Q24293191-F2C5B34B-42A9-4847-9547-097FFDAA0E3BQ24296754-7C4993A3-99BD-466B-9A38-F03B946126B0Q38296552-1E93930D-CEA2-43A7-91C6-29581F111986Q39600826-351A78DD-0A13-4FB6-89F3-5298F5ED4A56Q40869447-0FCC9E65-7A4A-4816-8CE2-F3A3B6116F9FQ45186177-0053C46B-9178-4F5B-A23A-673780E355F5Q53376148-B5D10960-7E4E-4D15-8CDC-077369F4CA8E
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in CD33 molecule
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
CD33 molecule
@en
CD33 molecule
@nl
CD33
@fa
CD33
@it
CD33
@ru
CD33
@uk
CD33
@zh
Siglec-3
@de
type
label
CD33 molecule
@en
CD33 molecule
@nl
CD33
@fa
CD33
@it
CD33
@ru
CD33
@uk
CD33
@zh
Siglec-3
@de
altLabel
CD33 antigen (gp67)
@en
CD33 molecule transcript
@en
CD33
@en
Siglec-3
@en
gp67
@en
myeloid cell surface antigen CD33
@en
sialic acid-binding Ig-like lectin 3
@en
prefLabel
CD33 molecule
@en
CD33 molecule
@nl
CD33
@fa
CD33
@it
CD33
@ru
CD33
@uk
CD33
@zh
Siglec-3
@de
P129
P527
P637
P672
P680
P681
P682
P705
P352
P486
P6366
P129
P31
P352
P486
P527
P6366
P637
NP_001076087
NP_001171079
XP_011525833
XP_011525834
XP_016882997
XP_016882998
XP_016882999
P672
D12.776.503.921.400
D23.050.301.264.900.565
D23.101.100.900.565
P680
P681
P682
P702
P703
P705
ENSP00000262262
ENSP00000375673
ENSP00000403331
ENSP00000410126