P129
P688
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiencyThe Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathwayApolipoprotein specificity for lipid efflux by the human ABCAI transporterCharacterization of the ATPase cycle of human ABCA1: implications for its function as a regulator rather than an active transporterThe ATP binding cassette transporter A1 contributes to the secretion of interleukin 1beta from macrophages but not from monocytesImpaired platelet activation in familial high density lipoprotein deficiency (Tangier disease)The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteinsNaturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-IApolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporterSterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolismApolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporterThe ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier diseaseAssociation of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cellsMolecular interactions between apoE and ABCA1: impact on apoE lipidationReduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitusABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosisEfflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutantsMicroRNA-19b promotes macrophage cholesterol accumulation and aortic atherosclerosis by targeting ATP-binding cassette transporter A1Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in ATP binding cassette subfamily A member 1
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
ABCA 1
@de
ABCA1
@es
ABCA1
@uk
ATP binding cassette sous-famille A membre 1
@fr
ATP binding cassette subfamily A member 1
@en
ATP binding cassette subfamily A member 1
@nl
type
label
ABCA 1
@de
ABCA1
@es
ABCA1
@uk
ATP binding cassette sous-famille A membre 1
@fr
ATP binding cassette subfamily A member 1
@en
ATP binding cassette subfamily A member 1
@nl
altLabel
ABC-1
@en
ABCA1
@en
ATP-binding cassette 1
@en
ATP-binding cassette sub-family A member 1
@en
ATP-binding cassette transporter 1
@en
ATP-binding cassette transporter A1
@en
ATP-binding cassette, sub-family A (ABC1), member 1
@en
cholesterol efflux regulatory protein
@en
membrane-bound
@en
phospholipid-transporting ATPase ABCA1
@en
prefLabel
ABCA 1
@de
ABCA1
@es
ABCA1
@uk
ATP binding cassette sous-famille A membre 1
@fr
ATP binding cassette subfamily A member 1
@en
ATP binding cassette subfamily A member 1
@nl
P361
P527
P637
P680
P681
P682
P705
P352
P6366
P637
P129
P31
P352
P361
P6366
2777704780
2910439382
P637
XP_005251830
XP_005251833
XP_011516641
XP_011516642
XP_011516643
XP_011516644
XP_011516646
XP_016869867
XP_016869868
P680
P681
P682
P702
P703
P705
ENSP00000363865
ENSP00000363868
ENSP00000416623
P7260
3.A.1.211.14